DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fpgs and DFB

DIOPT Version :9

Sequence 1:	NP_572814.1	Gene:	Fpgs / 32212	FlyBaseID:	FBgn0030407	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_196217.2	Gene:	DFB / 830484	AraportID:	AT5G05980	Length:	571	Species:	Arabidopsis thaliana

Alignment Length:	520	Identity:	171/520 - (32%)
Similarity:	255/520 - (49%)	Gaps:	82/520 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 AFELAIKQLNSLQSNDAAIRNSMSNSRVDTKADTIKYLERSGLPLETVEQLSFIHVAGTKGKGST 159
            ::|.|:..|:||.:..:....|....|.:...|.:|.|:..    |.:.:::.||||||||||||
plant    66 SYEEALAALSSLITKRSRADKSNKGDRFELVFDYLKLLDLE----EDILKMNVIHVAGTKGKGST 126

  Fly   160 CALTESLLRHQGFRTGFFSSPHILFTNERIRIDGQLLSKDKFTEQFWKVYNRLWDLREHDHDMPA 224
            |..|||::|:.|||||.|:|||::...||.|:||..:|::||...||..||||.:....:..||.
plant   127 CTFTESIIRNYGFRTGLFTSPHLIDVRERFRLDGVDISEEKFLGYFWWCYNRLKERTNEEIPMPT 191

  Fly   225 YFKFLTILGFHVFVAENVDVVVLEVGIGGEHDCTNIVRNVRTVGITSLGLEHTELLGRTLPEIAW 289
            ||:||.:|.|.:|.||.||..:||||:||:.|.||.|:.....||:|||.:|.|:||.||.:||.
plant   192 YFRFLALLAFKIFAAEEVDAAILEVGLGGKFDATNAVQKPVVCGISSLGYDHMEILGDTLGKIAG 256

  Fly   290 QKAGIIKTGSHVFTHVTQP-ECLEVIRQRTKEHSATLYEVPPTEDYFRSKAYAPIWQTFSNLIR- 352
            :||||.|.|...|| |.|| |.:.|:.::..|....|..|.|..               :.|:.
plant   257 EKAGIFKLGVPAFT-VPQPDEAMRVLEEKASETEVNLEVVQPLT---------------ARLLSG 305

  Fly   353 -----------LNGSLAIQLAQDWLSQSGKQQHTPNEVKMD---PQLLDGLISTHWPGRCQLI-- 401
                       :|..||:.||..||.|.||.: .|:..:|.   .:.:.||.:....||.|::
plant   306 QKLGLDGEHQYVNAGLAVSLASIWLQQIGKLE-VPSRTQMSILPEKFIKGLATASLQGRAQVVPD 369

  Fly   402 EWHGMR------LHLDGAHTLESMEVCTDWFEKNVRDS---------VN---------------P 436
            ::...|      .:|||||:.||||.|..||...|:..         ||               .
plant   370 QYTESRTSGDLVFYLDGAHSPESMEACAKWFSVAVKGDNQSGSSGHLVNGSAGSSHDKWSNETCE 434

  Fly   437 KILIFNRTGESGFAPLLKLLNRTC-----DFDMVCFVPNLATSTPNAPSQVMVRFSPEMQLNRAR 496
            :||:||.........||..|...|     :|....||||::.......:..:....|::.|:...
plant   435 QILLFNCMSVRDPNLLLPHLKNMCAKYGVNFKKALFVPNMSVYHKVGTAADLPENDPQVDLSWQF 499

  Fly   497 IIASAWSDLCATEQ--KKD-----VGQVYNTLTDAFTAIRQRFPQATDNEGQLEVLVTGSIHLLG 554
            .:...|..|..:|:  :||     ..:|:.:|..|...:|....::: :..:.:||||||:||:|
plant   500 TLQKVWESLVQSERDGEKDGESDGNSEVFTSLPMAIKCLRDTVHESS-SATRFQVLVTGSLHLVG 563

Fly 555 554
plant 564 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fpgs	NP_572814.1	PLN02881	90..554	CDD:215476	170/518 (33%)
DFB	NP_196217.2	PLN02881	54..571	CDD:215476	171/520 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0285
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6997
Inparanoid	1	1.050	243	1.000	Inparanoid score	I1065
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840266at2759
OrthoFinder	1	1.000	-	-		FOG0001698
OrthoInspector	1	1.000	-	-		mtm1059
orthoMCL	1	0.900	-	-		OOG6_100496
Panther	1	1.100	-	-	LDO	PTHR11136
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2113
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830