DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fpgs and Fpgs

DIOPT Version :9

Sequence 1:	NP_572814.1	Gene:	Fpgs / 32212	FlyBaseID:	FBgn0030407	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_038961794.1	Gene:	Fpgs / 687266	RGDID:	1587713	Length:	676	Species:	Rattus norvegicus

Alignment Length:	646	Identity:	208/646 - (32%)
Similarity:	300/646 - (46%)	Gaps:	187/646 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 KDTNAAFELAIKQLNSLQSNDAA---IRNSMSNSRVDTKADTIKYLERSGLPLETVEQLSFIHVA 151
            ::.:..::.|::.||:||:|.:.   ::...|:.:...:|..: ||.||||.:|.:.||..|||.
  Rat    39 QEPSMEYQDAVRTLNTLQTNASCLEEVKRQRSDPQAQLEAMEV-YLARSGLQVEDLNQLKIIHVT 102

  Fly   152 GTKGKGSTCALTESLLRHQGFRTGFFSSPHILFTNERIRIDGQLLSKDKFTEQFWKVYNRLWDLR 216
            ||||||||||.||.:||:.|.:||||||||::...|||||:|:.:|.:.||:.||.:|.:|.:.:
  Rat   103 GTKGKGSTCAFTERILRNYGLKTGFFSSPHLVQVRERIRINGKPISPELFTKYFWHLYQQLEEFK 167

  Fly   217 EHDH-DMPAYFKFLTILGFHVFVAENVDVVVLEVGIGGEHDCTNIVRNVRTVGITSLGLEHTELL 280
            :..| .||:||:|||::.||||:.|.||:.|:||||||..|||||:|.....|::|||::||.||
  Rat   168 DDSHISMPSYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLL 232

  Fly   281 GRTLPEIAWQKAGIIKTGSHVFTHVTQPE-CLEVIRQRTKEHSATLYEVPPTEDYFRSKAYAPIW 344
            |.|:.:|||||.||.|.|...|| |.||| .|.|:|.|.::.|..||..||.|      |...:.
  Rat   233 GDTVEKIAWQKGGIFKPGVPAFT-VLQPEGPLAVLRDRAQQISCPLYLCPPLE------ALEQVG 290

  Fly   345 QTFSNLI-----RLNGSLAIQLAQDWLSQSGKQQHTPNEVKMD-----------------PQLLD 387
            ...|..:     |.|.:||:|||:.||.|  :..|...|:|..                 |.:..
  Rat   291 LPLSLGLEGEHQRHNAALALQLARCWLEQ--QNYHDIQELKASKPSIRWQLPLAPVFRPTPHMRR 353

  Fly   388 GLISTHWPGRCQLIEWHGMRLHLDGAHTLESMEVCTDWFEKNVRDSVNP------KILIFNRTGE 446
            ||..|.||||.|:::...:..:||||||..|::.|..|:.:::..|...      .||:||.||:
  Rat   354 GLRDTEWPGRTQVLQRGPVTWYLDGAHTTSSVQACVHWYCQSLERSRRTDGGHEVHILLFNSTGD 418

  Fly   447 SGFAPLLKLLNRTCDFDMVCFVPNLA--TSTPNA-------------PSQVMVRFS--------- 487
            ...|.||||| :.|.||...|.||:.  :|..||             |...:|:.|
  Rat   419 RDSAALLKLL-QPCHFDYAVFCPNVTEISSIGNAGFLGNAHTHMVRGPRGHVVKMSERALELEHQ 482

  Fly   488 --PEM----QLNRARIIASAWS-------DLC--------------------------ATEQKK- 512
              |.|    :|:.:|  ::.|:       |.|                          .|:|:.
  Rat   483 ALPPMTVSSRLHWSR--STVWTTNGVWCRDACRDQELSRCSLSLRPLSSPPLTCLVLDPTDQQNF 545

  Fly   513 --DVGQV----------YNTLTD------------------------------------AFTAI- 528
              .:.||          :|.|.:                                    .|:.|
  Rat   546 TVTLDQVLLRCLQHQKHWNCLAEKQASSNLWGSCGPESARPGSLLLAPHPPQPTSTSSLVFSCIS 610

  Fly   529 --------------------RQRFPQATDNEG--------QLEVLVTGSIHLLGAAISALD 561
                                |......|.|.|        .:.||||||:||:|.|:..||
  Rat   611 HALQWISQGRDPIFQPESPPRNLLNHPTANSGASILREAAAIHVLVTGSLHLVGGALRLLD 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fpgs	NP_572814.1	PLN02881	90..554	CDD:215476	204/637 (32%)
Fpgs	XP_038961794.1	PLN02881	42..670	CDD:215476	208/643 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4068
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6997
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4187
OMA	1	1.010	-	-		QHG51906
OrthoDB	1	1.010	-	-		D231485at33208
OrthoFinder	1	1.000	-	-		FOG0001698
OrthoInspector	1	1.000	-	-		otm45686
orthoMCL	1	0.900	-	-		OOG6_100496
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2113
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880