Protein Alignment HOXC4 and Scr

DIOPT Version :9

• Sequence 1: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 100/306 - (32%)
• Similarity: 131/306 - (42%)
• Gaps: 101/306 - (33%)

Human    15 PKFPPCEEYSQNSYIPEHSPEYYGRT-------------RESGFQHHH----------QELYPPP 56
            |..|.....:|.:|..:.:|:....|             ::...||.|          |:|....
  Fly    88 PNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQ 152

Human    57 PPRPSYPERQ--YSCTSLQG---PGNSRGHGPA------QAGHHHPEKSQSLCEPAPLSGASASP 110
            .|:....::|  .||.....   ||.|.|.|.:      .:.:.:...||||..|..||....||
  Fly   153 HPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISP 217

Human   111 SPAPPAC-----------------------------------------------------SQPAP 122
            ..:|.:.                                                     |....
  Fly   218 KLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSES 282

Human   123 DHPSSAASKQ---------PIVYPWMKKIHV--STVNPNYNGGEPKRSRTAYTRQQVLELEKEFH 176
            |..:.|.|.|         |.:|||||::|:  ||||.|   ||.||.||:|||.|.||||||||
  Fly   283 DSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNAN---GETKRQRTSYTRYQTLELEKEFH 344

Human   177 YNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKV 222
            :||||||||||||||:|||:|||||||||||||||||:|::.:..:
  Fly   345 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNI 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		31/197 (16%)
		Antp-type hexapeptide	135..140		3/4 (75%)
		Homeobox	159..213	CDD:395001	46/53 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		1/9 (11%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	46/52 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4116
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.960