DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXC4 and zen2

DIOPT Version :9

Sequence 1:NP_055435.2 Gene:HOXC4 / 3221 HGNCID:5126 Length:264 Species:Homo sapiens
Sequence 2:NP_476794.1 Gene:zen2 / 40827 FlyBaseID:FBgn0004054 Length:252 Species:Drosophila melanogaster


Alignment Length:157 Identity:54/157 - (34%)
Similarity:73/157 - (46%) Gaps:45/157 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   134 IVYPWMK-KIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSE 197
            ::||.:: .:..:......:..:.||||||::..|::|||:|||.|:||.|.|||||:..|.|:|
  Fly    20 MMYPCVELNVEAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTE 84

Human   198 RQIKIWFQNRRMKWKKDH----------------------------------RLPNTKVRSAPPA 228
            ||:||||||||||.||..                                  |..||.|.:||  
  Fly    85 RQVKIWFQNRRMKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAP-- 147

Human   229 GAAPSTLSAATPGTSEDHSQSATPPEQ 255
                  |.....|..|:  ...|||.|
  Fly   148 ------LRQVDHGVLEE--GQITPPYQ 166

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXC4NP_055435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..130
Antp-type hexapeptide 135..140 2/4 (50%)
Homeobox 159..213 CDD:395001 35/53 (66%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 214..264 13/76 (17%)
zen2NP_476794.1 Homeobox 46..99 CDD:278475 35/52 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.810

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