|
Fly 3 HNNAPWL--PPHQQQQQQAPQQH-PTPQQQHAMPQQQQTLPAQ---------------QQQQQVY 49
|:::|.| |......|.|...| |:|...|..|..:..:|.. .||.:.|
Rat 225 HHHSPCLEGPVQDMGPQAASLPHFPSPSSLHEGPGHESRVPQTFTPASLASGEGNEIVHQQSKNY 289
Fly 50 AS------QMFQQHQ--PNYWPEDQHQQQQQPQSLNYNNYFPGQQQQHPMQQQQLPPQQQLPPQQ 106
.| ..|:|:. .|.|...:.:|. ||..::| .|.|..
Rat 290 PSSSFPPKHSFEQNSRVGNMWASAEFRQN------------PGVNKEH-----------LLDPAH 331
Fly 107 QQPTQQQHTIQQQLYYP-------------------------TQQQPQV---PAPAEPALD--SF 141
..|..|.::.:.|:::| |:.:..: .|..:..|| ||
Rat 332 VNPFTQGNSPENQVHHPPVAATNHALQEAASGALSMFFQGEETENEENLSSEKAGLDDRLDSGSF 396
Fly 142 DNNNSGG-----GGGG-----------------------------GRSDGWGD---------WGD 163
.:.:..| |.|| ..:|.||| .|.
Rat 397 SSTSRLGHPPLPGAGGVYQAAQEGDVQPYFSQFVGIRHDKQTTMTPANDAWGDIPGAGTHCASGP 461
Fly 164 WNDNSNN----NNSN-------------------------------GTDGLLEPTGQLLE----- 188
..:|..| .|.. .|.||....|..||
Rat 462 QCENVENLEFVQNQEVLPRETVNVDPFSPSDQFRYGPLPGPAASRPVTSGLTRGGGLNLEAPDMP 526
Fly 189 ------DSFNVQSSQGSWQAFATSNNVNNNGELPPP--ANPQ---STSLQQQ--PLNQQSIPLLH 240
|| .|::.:|:....|| |.|| .|.:||: .|...:.....
Rat 527 LHPTRPDS--------------VSSSYSNHSHRSPPGSARPQELVGTFIQQEVGKLEDDTSGSFF 577
Fly 241 QQPQSPPELGQEPELDAIVPPQAFQNQPPTAAPP-PTSL--TSFSAQMTAVGSPIYAVGASSA-- 300
:|..|.|..|:..|:.......:..:||.|.:|| ||.: ||.::....|.|.:..|....|
Rat 578 KQIDSSPVGGETDEMTRSQNYCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADR 642
Fly 301 ---------------HSAGVGASPAPPTGVVAPPAHLAGIGAPPAHLAGVGASPAPSALVGASPA 350
|.|.|....|.|..:..||.::..:.||. |.|.|.:..|.:..
Rat 643 ANMVVEVRGTQNCQKHGAAVLPPDATPGNLEQPPDNMETLCAPQ-------ACPLPLSTTGEAGQ 700
Fly 351 PIIGVGAPPVG-APPVGAPPADATTIAPPAALPPSI-------VPSSGSNPFKRSTGLNKRVNIM 407
.:.....||:. ..|:....:.|....|.....|:. :|..|. |::
Rat 701 LVSHTAGPPLDTVRPMPDKRSSARAQGPVKCESPATTLWAQNELPDFGG-------------NVL 752
Fly 408 ADPAAGA---PSPPAP------------------AAAIAPVAPVAP--------IPPPADQLFGM 443
..|||.| |..|.| :.::.|:....| .||...:...:
Rat 753 LAPAAPALYVPVKPKPSEVVHHPEKGMSGQQSWKSGSVPPLQNQDPPGASENLENPPKVGEEEAL 817
Fly 444 PAEAHGEGFNLIAAPPVEASLGTP-----------LSAPIPAPIPVPN----------------- 480
|.:|.....:|:::||.|:....| |:.||...:.:||
Rat 818 PLQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLPNPNEKNQCWGDAVVGEKS 882
Fly 481 --------------ASLYASPA-----------VPQAFAHLEPDNQEVL-SAPNDERAQYL---- 515
|:|.|.|| |.|..|.....:.|:: |.|.....|.|
Rat 883 MVSTRALGADHEEHAALSAIPASTVTGSSLPNSVTQNCAPRGSGSSEMIASQPASWLVQQLSPQI 947
Fly 516 -QTSHLSEQLGEGE-ADQDAG---LLPPPGLSRLVLG--------QPE-----LDSQQQRQV--- 559
|:.|.:.:.|..| .:..|. :|.||..|.::.. .|| ||....|.:
Rat 948 PQSQHPNAEKGPSEFVNSPANGSVMLAPPANSAVIPNSNKGYHSRNPEEAIGALDFTLSRTLENP 1012
Fly 560 ----------TGATEQPPLNVAQAA--ALHMQER-----RADGEDTSDGEQQVRNIQTPPRRVVT 607
:.|::||..|..:.: .||.|:. ..|.:|....|:....:..||.:
Rat 1013 VRMCSPSHSNSPASQQPLANHPRQSGPGLHNQDHFYQQVTKDAQDHRSLERGQSELVPPPPQ--- 1074
Fly 608 GVETNAPSLREQREVVLDGENLEDREAIPPPTLAELPTTSVHHNILPDEAEQLHHNNPPQAMTPL 672
|:|....| .|.|.|:..|.|.|. .::|.| ..|..:..|:
Rat 1075 ----NSPQQVPQ-------------AACPEPSNPESPPTQ-------GQSEGL--VQPSASPAPV 1113
Fly 673 N-AQQPHQQQSTLQQQHQQHSTTQQEKKRAAVGRR--------TT---ASLDLESDESDEFLQSE 725
| .|||...||: ..|.|.....:|||... || |..||
Rat 1114 NTGQQPQPPQSS------SASVTSTNSNQAAVRSEQPWLHPPPTTFGPAPQDL------------ 1160
Fly 726 RERDRERERRDLMEERHSRGRSHSHY--PYEG------ETEDSVRGAA---HHETKSLRETHHKR 779
.|:.:| |||. ....|..||| :.:...|.|..: |
Rat 1161 --------------------ASYYYYRPPYEAYQSPYPSPYPSDPGAASLYYQDIYGLYEPRY-R 1204
Fly 780 NHDSARSRRHQDPKVERERERDRERDRTWRRRSNKYHSGGEDPDRSYDHSRRYNNSNYEGESD-- 842
.:||:.| ...|..|..|.:|...|.| ::|....|.:.|......:.|.:...||
Rat 1205 PYDSSAS-------AYAENHRYSEPERPSSRAS--HYSDQLTPRQGYPEGYYNSKSGWSSHSDYY 1260
Fly 843 ----NPEYNHMGDAELD---GSGGRSSKTSRHRRSAAEEDFDDYERERNRSRRSTKPQSSAEKSR 900
:.:|::......| ||..|..:| ..||...:.|.|.|.::
Rat 1261 ANYYSGQYDYGDPGRWDRYYGSRFRDPRT-WDRRYWYDSDHDPYRKD------------------ 1306
Fly 901 SSGGRRNYENSGRSARADDGRRRYQDQRNPGAQYPVSATGYVPYGMYEQMSRNPQVYADMYAKFY 965
||..|.|..:.|| ..|| |.|..|: :....::.|:| |
Rat 1307 ------NYAYSDRPEKCDD-HWRY-DPRFTGS-----------FDDDTELHRDP----------Y 1342
Fly 966 GQMINSMNAAVSAAASKGGVPAGAGVIPGLMPSAVPVSAAQLVAATSGGSVSGSSEAAMLRERER 1030
|:.::.. |:.....|..||.
Rat 1343 GEEVDRR------------------------------------------SIHSEHSARSLRS--- 1362
Fly 1031 YTHAYITQANEFHRHQYKELIYQQQQQQQQQQQQQQQREDHLNSSFSVAEDNASFYGSHGGGSIY 1095
||:..::.:....|.::..|| |..|:. ..||...|..||.:
Rat 1363 -THSLPSRRSSLSSHSHQSQIY---------------RSHHVT--------GGSFEAPHAPGSFH 1403
Fly 1096 NQYQSYPLSSARSLSNLNGDGRNSRCGPYYAGSECGLDIRAAADAAPSTYGGVAGTAGPVTNTAV 1160
..| :.....||.:| |...|. |...|.|:.|......
Rat 1404 GDY-----AYGTYASNFSG-----------------------AHGFPE-YSYPADTSWPAAEQVP 1439
Fly 1161 ARPPRRRTPLQFSRPHLVASYAM-SLLLKVKPKYAGRGR--------LRNDVEVAPPRIRDGTSS 1216
:|| .:|.:|:.||:.|.:.. ..||||.|.....|: |...::..|.: .
Rat 1440 SRP---TSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQ------E 1495
Fly 1217 LLRMYPGPLQGRKLHKDKIISFCKEQIRLGPTKGCTALYATQKKPQGSVTKYRASHALMWHLLIL 1281
.:|.:||||.....||..:|:|.:.: ||:.....|:.. :.|.:|:|:.:||
Rat 1496 EMRSFPGPLGKDDTHKVDVINFAQNK-------------ATKCLQNESLID-KESASLLWNFIIL 1546
Fly 1282 LLRQNGYIADTDVGDLLLENQQ------EYPYDPSEFEAENEPDADAEQDAAAPADKTVDSDLDS 1340
|.||||.:..||:.:|||.:.: :.|.:.:..:..||.....|::.:..|..:..:|
Rat 1547 LCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTD--- 1608
Fly 1341 ESAAGVTPAEPLAAGAATSSINGADAANAATPLSEQAATDKFRSYVLRGNVEEALQWATDNGLWT 1405
:...|||: |.:: |::||..:|.|..::||:.|..||||.
Rat 1609 -------------SQTVTSSV-----------LEKE--TERFRELLLYGRKKDALESAMKNGLWG 1647
Fly 1406 HAFFLALYEDRYALTDVAQKFLNRAIKANDPLQTLYQMKSCHTPACVSQLRDEQWGDWRSHLSIL 1470
||..||...|......|..:|.| ::..||||||:||:.|...||..:...||:|||||.||:::
Rat 1648 HALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMV 1711
Fly 1471 VTNKSRQPEYDRSSVVALGDTLFQRGDIYAAHFCYLVAQEEFGRYDSSATELTTLTANVPRLILL 1535
::|.:...:.:..::..:||||..:|.:.|||||||:||..||.| |:.|| :|:|:
Rat 1712 LSNLNNNMDVESRTMATMGDTLASKGLLDAAHFCYLMAQVGFGVY----TKKTT------KLVLI 1766
Fly 1536 GSSHYKHFNEFASNEAIIMTEIYEYARSLFDPKFSIAHFQHYKFLLATRILDYGQHFRCTNYLEQ 1600
||:|...|.:||:||||..||.||||:||.....|:.:||.:||:...|:.:.|...:..:|.|.
Rat 1767 GSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCRLAEMGLATQAFHYCEV 1831
Fly 1601 IARHIELKPESYDSNFIQRVCGLAERLRYHDPILINR---VSFASPPNATSKDSAAAEEKAWLRQ 1662
||:.:..:|.:|....|.::..:|.:||..||.|..: .||..| |||.|
Rat 1832 IAKSVLTQPTAYSPVLISQLIQMASQLRLFDPQLKEKPEEESFVEP--------------AWLVQ 1882
Fly 1663 LRSLAYVQPQQEQLQQLQQNQQVQQEQNDIDQQFAEVNKQFRELNMQYESNSNMENTLQPQLPPV 1727
| |...:|:|:...:..:.....|| ....|.|.:| ||..|.:
Rat 1883 L---------QHVERQIQEGTVLWNQDGTEPQQ------------CHITSGSEVE---QPDGPGL 1923
Fly 1728 DQQP-PQQQQQVLSESYQQPTQQYYEPPPQAPTESDPYGQGQPSY-------------------- 1771
:||. |:....:|..| |:.........||.......|||::
Rat 1924 NQQAGPRADNPLLMPS----TEPLVHSVQLLPTAPQTLPDGQPAHLARVPMFPVPMSRPPLELSA 1984
Fly 1772 -YDPNAGQLHY------DPNAAQHQYDQQQPQPQPTPSYGQIEPG-TEAYQPGQATADPAAVPSG 1828
|.|....|.: || |..| ..|..|..||...:..|. .||..| ||..||.|
Rat 1985 AYGPPGSVLGFPESSRSDP-AVLH---PGQALPPATPGLQESGPPLQEARSP-----DPEMVPQG 2040
Fly 1829 YGYDYWSGTQQPPYGDEPNENQ----AALKDEEEEDEEQDEQQILQYAKQQILQ----------- 1878
....: .|| ||.|.: .|........::.:...:.......:.:
Rat 2041 SPVRH-----SPP---EPREEEFGKNVADLGSSRTAQDSETSPVWDLGSSSLTRAPSLTPDSEGK 2097
Fly 1879 ---QTKQQQLQQEQHTRSNGAASINNRFKSNALKQERSSGSL----RKRQ-------EASRTATI 1929
|..:::.::.:.|.|..:..:..:.::.|...:..:.|: :|.| |..:.|.
Rat 2098 KPAQAVKKEPKEPKKTESWFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAP- 2161
Fly 1930 AAAAAAIAQITPATVAAAATPPAASAKAFNLNDVSSFSSTNKRHQATSSSNNRSSSNQAAAAAAA 1994
.....:..::..|.....|.||.||...| |..:...|.:.....|...:.....|.|.|
Rat 2162 PPPPTSFPRVPQAAPTGPAGPPMASVNVF------SRKAGGSRARYVDVLNPSGTQRSEPALAPA 2220
Fly 1995 TKAAAIATVPAAPNQLLSCRKSNSQNSPYLAT---------PKTLTTPTRFIAAKAATVTATPTA 2050
...|.:|.:| .|:.|........::.|...| .::...|| .:|..|::|.:|
Rat 2221 DFFAPLAPLP-IPSNLFVPNPDAEESQPADGTGCRGQAPAGTQSKAEPT----LEAKVVSSTVSA 2280
Fly 2051 PATSTTTSTTI-GARGSSTKRVYFNLPSTIAESEQEFEHELDYDEEMEEENSMALAQAKPNVHLA 2114
|....:.|... |::|....|. .:|.|...|..:.| |:...|. ..|.|.|
Rat 2281 PGPELSPSKPADGSQGGELSRC-SSLSSLSQEVSRHF-HQAPGDH--------CPAGATP----- 2330
Fly 2115 RKPHIVFNGTYPIDMPLTQGQSQLKSNSYDP 2145
.|:.|...|....|:.:.|.:..|
Rat 2331 -------GGSVPFYNPAQLVQASVTSGTSRP 2354
| 
