Protein Alignment CG1824 and mdlA

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_414982.1
• Gene: mdlA / 945092
• ECOCYCID: G6248
• Length: 590
• Species: Escherichia coli
• Alignment Length: 634
• Identity: 188/634 - (29%)
• Similarity: 303/634 - (47%)
• Gaps: 83/634 - (13%)

  Fly   118 DWKRLWTYLEPHLWELIGAVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDVS 182
            :|:|   ||        |||...:|:|.:.:..|.::|.:|:.:.....|      ....:..::
E. coli    14 EWRR---YL--------GAVALLVIIAMLQLVPPKVVGIVVDGVTEQHFT------TGQILMWIA 61

  Fly   183 KPASNLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTA 247
            ......:.:|:|:    :::..||.....|:|.::|:|.:.|:..|...|:..:|||:|:.|.|.
E. coli    62 TMVLIAVVVYLLR----YVWRVLLFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATN 122

  Fly   248 DVQDFKTSFKQFVSQG-LRSAAQLIGGSISLFM----ISPHMAAIALASVPCVVMFMTYLGKKLR 307
            ||.  :..|.  ..:| |.....|:.|...|.|    ||..:...:|..:|.:.:.:...|..|.
E. coli   123 DVD--RVVFA--AGEGVLTLVDSLVMGCAVLIMMSTQISWQLTLFSLLPMPVMAIMIKRNGDALH 183

  Fly   308 SLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNE-------AARLAQKLGYGI 365
            ...|.:||.........:|:|::||.:::...|.|:..||.|:..:       .||:..:....|
E. coli   184 ERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARIDARFDPTI 248

  Fly   366 AIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMI---- 426
            .|..|:.|       |..:..|..::...||:.|.|.:|:              :.||.||
E. coli   249 YIAIGMAN-------LLAIGGGSWMVVQGSLTLGQLTSFM--------------MYLGLMIWPML 292

  Fly   427 ----------RGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLK 481
                      ||.:|.||:...|:..|.|. .....:|:.|  ||:......|.|| |.||..|:
E. coli   293 ALAWMFNIVERGSAAYSRIRAMLAEAPVVN-DGSEPVPEGR--GELDVNIHQFTYP-QTDHPALE 353

  Fly   482 DFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQ 546
            :.:..|:|||.:.:.|.:||||||:.||::|.::.|.|:|:.....|:.:.....||. |..:.|
E. coli   354 NVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSR-LAVVSQ 417

  Fly   547 QPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIA 611
            .|.||..::..||..|.|:|.::::...|||:..||.:..||.||.|.|||||..|||||:|||:
E. coli   418 TPFLFSDTVANNIALGCPNATQQEIEHVARLASVHDDILRLPQGYDTEVGERGVMLSGGQKQRIS 482

  Fly   612 IARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGR 676
            ||||||.|..|||||:|.||:|..:|.::...|....|.||.::.|||||.:..|..|:|:..|.
E. coli   483 IARALLVNAEILILDDALSAVDGRTEHQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGH 547

  Fly   677 VVETGKHDELMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQATA 725
            :.:.|.||.|..:.|.|.::.|.|:..      .|::|....:|:...|
E. coli   548 IAQRGNHDVLAQQSGWYRDMYRYQQLE------AALDDAPENREEAVDA 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	184/608 (30%)
mdlA	NP_414982.1	PRK10789	22..590	CDD:182732	181/613 (30%)