Protein Alignment CG1824 and mdlB

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_414983.1
• Gene: mdlB / 945088
• ECOCYCID: EG11622
• Length: 593
• Species: Escherichia coli
• Alignment Length: 623
• Identity: 188/623 - (30%)
• Similarity: 317/623 - (50%)
• Gaps: 63/623 - (10%)

  Fly   120 KRLWTYLEPHLWELIGAVCAALIVAYINIRIPNLLGDLV-NTLARYANTYVMDPINNSFVKDVSK 183
            |||..|..|....|..||....:.|...:..|.|:...: |.:|:          ||..:|.|:.
E. coli    12 KRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAK----------NNLPLKVVAG 66

  Fly   184 PASNLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTAD 248
            .|:..:.|.:..:|..:....|.:|....:..::|.|:....:.|.::.||....|::::|:|.|
E. coli    67 LAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTND 131

  Fly   249 VQDFKTSFKQFVSQGLRSAAQLIGGS-ISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKS 312
            .:..:..:...|:..||||| |:|.. :::|.:...||.:|:...|.|::.|....:....:.:.
E. coli   132 TEVIRDLYVTVVATVLRSAA-LVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRR 195

  Fly   313 SQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLGYGIAIFQ--GLTNFF 375
            .:|..........|.::.:..::    ::|:...|.....||:|     .:.:|..|  .|..|.
E. coli   196 VRAYLADINDGFNEIINGMSVIQ----QFRQQARFGERMGEASR-----SHYMARMQTLRLDGFL 251

  Fly   376 LNTL--VLSTLFMGGHLM-----STESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGS 433
            |..|  :.|:|.:.|.||     ::.::..|.|.||:.....:...|.:.:.....:.:.:.||.
E. coli   252 LRPLLSLFSSLILCGLLMLFGFSASGTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGE 316

  Fly   434 RVFEFLSLQPQVELLRGYIIPQERL--------HGEIRFENVSFAYPMQPDHLVLKDFSLTLRPG 490
            |||         ||:.|   |:::.        .|.|..:||||||  :.|:||||:.:|::...
E. coli   317 RVF---------ELMDG---PRQQYGNDDRPLQSGTIEVDNVSFAY--RDDNLVLKNINLSVPSR 367

  Fly   491 QTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSI 555
            ..|||||.:||||||:|||:..:|..:.|.|:|||..||.:|...||..| ..::|.||:...:.
E. coli   368 NFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSALRQGV-AMVQQDPVVLADTF 431

  Fly   556 LENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNP 620
            |.|:..|: |..||.|:.|....|..:...::.||..|.:||:|..||.||:|.:|:||.|::.|
E. coli   432 LANVTLGR-DISEERVWQALETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETP 495

  Fly   621 RILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDE 685
            :||||||||:::|:.:|..:|.||..|.::.|.:|||||||||.:||.|:||.:|:.||.|.|.:
E. coli   496 QILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQ 560

  Fly   686 LMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQA 723
            |:..:|.|:::        .|.|:...|...:|:|:::
E. coli   561 LLAAQGRYWQM--------YQLQLAGEELAASVREEES 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	183/600 (31%)
mdlB	NP_414983.1	PRK10790	1..592	CDD:182733	188/623 (30%)