Protein Alignment CG1824 and MDL1

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_013289.1
• Gene: MDL1 / 850885
• SGDID: S000004178
• Length: 695
• Species: Saccharomyces cerevisiae
• Alignment Length: 594
• Identity: 205/594 - (34%)
• Similarity: 317/594 - (53%)
• Gaps: 44/594 - (7%)

  Fly   118 DWKRLWTYLEPHLWELIG-AVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDV 181
            |.|||:...:|.. :.|| |:...||.:.:::.:|:::|.|            :|..:.|..:|.
Yeast    88 DIKRLFVLSKPES-KYIGLALLLILISSSVSMAVPSVIGKL------------LDLASESDGEDE 139

  Fly   182 SKPASNLLSLYMLQSGFTFM-------------YIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFF 233
            ....||.|..:..:..||.:             .|.:|...||::.|::|.......:.||..|.
Yeast   140 EGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFL 204

  Fly   234 DENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQ-LIGGSISLFMISPHMAAIALASVPCVVM 297
            |.||.|:|::||::|......|..|.||.|.|:..| .:|..:..|:.......:.:.:.|...|
Yeast   205 DTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAM 269

  Fly   298 FMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLG 362
            .:.| |:|:|:||:..|......|.|.||.|:..||:::...|..|::.:..|......:..|..
Yeast   270 ALIY-GRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEA 333

  Fly   363 YGIAIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIR 427
            ....:|.|.|....||.:||.|.:|..::.:.|::.|.|.:|::.:.....||...|.....:::
Yeast   334 VTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMK 398

  Fly   428 GMSAGSRVFEFLSLQPQVELLRGYI--IPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPG 490
            |..|.:||||....:|   |:|..|  .|.......|.|:||||.||.:|.|.:.||.::|::||
Yeast   399 GAGAAARVFELNDRKP---LIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPG 460

  Fly   491 QTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRS--NVLGFIEQQPVLFGT 553
            :.|..||.|||||||||||:.|:|:.::|:|:...   .||..:.||.  .::|:::|:|:||..
Yeast   461 EHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGD---EDIRNFNLRKYRRLIGYVQQEPLLFNG 522

  Fly   554 SILENIRYG-KPDAGEED--VYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARA 615
            :||:||.|. .|:..|:|  :..|...:....|:...|||..|.||.||.||||||:||||:|||
Yeast   523 TILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARA 587

  Fly   616 LLKNPRILILDEATSALDATSEAEVQKALDTVVQNR-TTLVIAHRLSTIRNADLIVVLDQ-GRVV 678
            .|.:|.:|||||||||||:.||..|.|.|...|:.. ||:.||||||||:::..::||.: |.||
Yeast   588 FLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFTTISIAHRLSTIKHSTRVIVLGKHGSVV 652

  Fly   679 ETGKHDELM 687
            |||...:|:
Yeast   653 ETGSFRDLI 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	204/593 (34%)
MDL1	NP_013289.1	MdlB	82..679	CDD:440747	205/594 (35%)