DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1824 and ABCB26

DIOPT Version :9

Sequence 1:	NP_572810.1	Gene:	CG1824 / 32208	FlyBaseID:	FBgn0030403	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_177218.3	Gene:	ABCB26 / 843398	AraportID:	AT1G70610	Length:	700	Species:	Arabidopsis thaliana

Alignment Length:	747	Identity:	226/747 - (30%)
Similarity:	369/747 - (49%)	Gaps:	112/747 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LRLLVSNCG--RSSDIFSRHLLQPTQQPLPRLQNAARLMRQHLRGTNAPQPPAIPPTNAS----R 60
            :|:.:..|.  .:||...|..|:..:.  |||..:.:...::.|         :|..|.|    .
plant    13 IRVSLHRCSVITTSDTIRRKNLRFVRN--PRLSFSLQSSTRNYR---------LPSINCSTVNGA 66

  Fly    61 LLQTTRLLVWGGGSLAIG-------------LGARSWWAGHRGAIVHCEGSRLAIRKEEEEEDTA 112
            :.:|.......|.::::.             |...|||:                ..:|.:....
plant    67 VAETAEYYEGEGDNVSLAEKIRQCIDFLRTILPGGSWWS----------------FSDEVDGRFI 115

  Fly   113 SEQHFDWK---RLWTYLEPHLWELIGAVCAALIVAYINIRIPNLL---------GDLVNTLARYA 165
            ::....|:   |:|..:....|.:..|....::.|...|.||:.|         ||:.
plant   116 AKPVTVWRALSRMWELVAEDRWVIFAAFSTLIVAALSEITIPHFLTASIFSAQSGDIA------- 173

  Fly   166 NTYVMDPINNSFVKDVSKPASNLLSLYM---LQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVV 227
                      .|.::|..    |::|.:   :.||....:..:.:.:   :..:||:.|::.::.
plant   174 ----------VFHRNVKL----LVTLCVTSGICSGIRGCFFGIANMI---LVKRMRETLYSTLLF 221

  Fly   228 QDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMIS-P-HMAAIALA 290
            |||:|||....|:|.:||.:|.|.........::...|:..|..|..|.|.::| | .:..:.:.
plant   222 QDISFFDSQTVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQGTGALIYLLILSWPLGLCTLVIC 286

  Fly   291 SVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAA 355
            .:...|||:  .|...:..:|..|.....|..|.:|..|.:||||....|.:|.:.:.......|
plant   287 CILAAVMFV--YGMYQKKTAKLIQEITASANEVAQETYSLMRTVRVYGTEKQEFKRYNHWLQRLA 349

  Fly   356 --RLAQKLGYGIAIFQGLTNFFLNTLVLST----LFMGGHLMSTESLSPGALMAFLVASQGVQRS 414
              .|.|...|||      .|:..|||..:|    :.:||..:....::...|..||:.|:.:..:
plant   350 DISLRQSAAYGI------WNWSFNTLYHATQIIAVLVGGLSILAGQITAEQLTKFLLYSEWLIYA 408

  Fly   415 LAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELL-RGYIIPQERLHGEIRFENVSFAYPMQPDHL 478
            .......|.::::.:.|..:||:.:.|:|..:.: :|..:  :||.|.|.|.:|||:||.:.:..
plant   409 TWWVGDNLSSLMQSVGASEKVFQMMDLKPSDQFISKGTRL--QRLTGHIEFVDVSFSYPSRDEVA 471

  Fly   479 VLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGF 543
            |:::.::::.||:.||:||.|||||||:.:|:.:.|||::|.|.|||..|.::...|||..: |:
plant   472 VVQNVNISVHPGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLDGVPLKELDVKWLRQRI-GY 535

  Fly   544 IEQQPVLFGTSILENIRYG-KPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQR 607
            :.|:|.||.|.|..||:|| ..:..:||:.:||:.:.:|||:||||:||.|.|.:  ..|||||:
plant   536 VGQEPKLFRTDISSNIKYGCDRNISQEDIISAAKQAYAHDFITALPNGYNTIVDD--DLLSGGQK 598

  Fly   608 QRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTV----VQNRTTLVIAHRLSTIRNADL 668
            ||||||||:|::|||||||||||||||.||..|:..|.::    ...|:.:|||||||||:.||.
plant   599 QRIAIARAILRDPRILILDEATSALDAESEHNVKGVLRSIGNDSATKRSVIVIAHRLSTIQAADR 663

  Fly   669 IVVLDQGRVVETGKHDELMGKRGLYFELVRQQ 700
            ||.:|.|||||.|.|.||:.|.|||..|.::|
plant   664 IVAMDSGRVVEMGSHKELLSKDGLYARLTKRQ 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..701	CDD:224055	206/611 (34%)
		ABC_membrane	137..415	CDD:279056	68/297 (23%)
		ABC_MTABC3_MDL1_MDL2	462..700	CDD:213216	122/242 (50%)
ABCB26	NP_177218.3	3a01208	76..691	CDD:273363	210/667 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0058
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54509
OrthoDB	1	1.010	-	-		D684058at2759
OrthoFinder	1	1.000	-	-		FOG0000243
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830