DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1824 and ABCB22

DIOPT Version :9

Sequence 1:	NP_572810.1	Gene:	CG1824 / 32208	FlyBaseID:	FBgn0030403	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001327523.1	Gene:	ABCB22 / 822471	AraportID:	AT3G28415	Length:	1229	Species:	Arabidopsis thaliana

Alignment Length:	644	Identity:	217/644 - (33%)
Similarity:	339/644 - (52%)	Gaps:	58/644 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 LIGAVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDVSKPASNLLSLYMLQSG 197
            |||||....|...|......||.|:.::...          :.:|:..:.|.|..|  ||:..:.
plant    26 LIGAVGDGFITPIIFFITGLLLNDIGDSSFG----------DKTFMHAIMKNAVAL--LYVAGAS 78

  Fly   198 FTFMYI--YLLSRVGEQMAAKMRQDLFTQIVVQDIAFFD--ENRTGELVNRLTAD---VQD-FKT 254
            ....::  |..:|.||:.|::||:.....::.||:.:||  ...|.:::..:::|   :|| ...
plant    79 LVICFVEGYCWTRTGERQASRMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDTLVIQDVLSE 143

  Fly   255 SFKQFVSQGLRSAAQLIGGSISLFMIS----PHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQA 315
            ....|:.......|..|.|.|.|:.::    |....:.:..:.|        |:.|.::|:..:.
plant   144 KLPNFLMSASAFVASYIVGFIMLWRLTIVGFPFFILLLIPGLMC--------GRALINISRKIRE 200

  Fly   316 QAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLA--QKLGYGIAI-FQGLTNFFLN 377
            :...|..:.|:|:|.:|||.:...|.:.:..|.|....:.:|.  |.:..|||| ..|:|.....
plant   201 EYNEAGSIAEQAISLVRTVYAFGSERKMISKFSAALEGSVKLGLRQGIAKGIAIGSNGVTYAIWG 265

  Fly   378 TLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQ 442
            .:.    :.|..::.......|.:.|.::.......||.:|...|......:.||.|:.|.:...
plant   266 FMT----WYGSRMVMYHGAKGGTIFAVIICITYGGTSLGRGLSNLKYFSEAVVAGERIIEVIKRV 326

  Fly   443 PQVEL--LRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKST 505
            |.::.  .||.::  |.:.||::|::|.|.|..:|:..:..|..|.:..|::|||||.|||||||
plant   327 PDIDSDNPRGQVL--ENIKGEVQFKHVKFMYSSRPETPIFDDLCLRIPSGKSVALVGGSGSGKST 389

  Fly   506 IASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEED 570
            :.||::|||:|..|.|.:||..:..:...||||. :|.:.|:|.||.|||.|||.:||.||..::
plant   390 VISLLQRFYDPIVGEILIDGVSIKKLQVKWLRSQ-MGLVSQEPALFATSIEENILFGKEDASFDE 453

  Fly   571 VYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDAT 635
            |..||:.|.:|||::..|.||.|.|||||.|:||||:|||:||||::|:|.:|:|||||||||:.
plant   454 VVEAAKSSNAHDFISQFPLGYKTQVGERGVQMSGGQKQRISIARAIIKSPTLLLLDEATSALDSE 518

  Fly   636 SEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELM-GKRGLYFELVRQ 699
            ||..||:|||.....|||:|||||||||||.|:|.|...|::||||.|:||| ...|.|..|||.
plant   519 SERVVQEALDNATIGRTTIVIAHRLSTIRNVDVICVFKNGQIVETGSHEELMENVDGQYTSLVRL 583

  Fly   700 QERRDIQEQVQAVEDV-VAVKEQQAT--------ATETSTAATIATAAETSAATVTVGS 749
            |    |.|..::.::| |:::|.|.:        ::..|..:..:..|.:|..|...||
plant   584 Q----IMENEESNDNVSVSMREGQFSNFNKDVKYSSRLSIQSRSSLFATSSIDTNLAGS 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..701	CDD:224055	204/585 (35%)
		ABC_membrane	137..415	CDD:279056	59/292 (20%)
		ABC_MTABC3_MDL1_MDL2	462..700	CDD:213216	127/238 (53%)
ABCB22	NP_001327523.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910