Protein Alignment CG1824 and ABCB4

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_182223.1
• Gene: ABCB4 / 819314
• AraportID: AT2G47000
• Length: 1286
• Species: Arabidopsis thaliana
• Alignment Length: 675
• Identity: 238/675 - (35%)
• Similarity: 368/675 - (54%)
• Gaps: 58/675 - (8%)

  Fly   104 KEEEEE----DTASEQHFDWK-----RLWTYLEPHLWEL-----IGAVCAALIVAYINIRIPNLL 154
            ||||||    :...|:|...|     :|:.:.:...:.|     :|::...|....:.:    |.
plant    24 KEEEEEVKKTEKKDEEHEKTKTVPFYKLFAFADSFDFLLMILGTLGSIGNGLGFPLMTL----LF 84

  Fly   155 GDLVNTLARYANTYVMDPINNSFVKDVSKPASNLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQ 219
            |||::.... ..|...|.::...:|.|........:.::..||      :::|  ||:.||::|.
plant    85 GDLIDAFGE-NQTNTTDKVSKVALKFVWLGIGTFAAAFLQLSG------WMIS--GERQAARIRS 140

  Fly   220 DLFTQIVVQDIAFFD-ENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPH 283
            .....|:.||||||| :..|||:|.|::.|....:.:..:.|.:.::..|..:||.:..|:....
plant   141 LYLKTILRQDIAFFDIDTNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLLATFVGGFVIAFVRGWL 205

  Fly   284 MAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFE 348
            :..:.|:|:|.:||....|...:...:...|....:|..|.|:.:.:||||.|...|.:.:..:
plant   206 LTLVMLSSIPLLVMAGALLAIVIAKTASRGQTAYAKAATVVEQTIGSIRTVASFTGEKQAISNY- 269

  Fly   349 AETNEAARLAQKLGYGIAIFQGLTNFFLNTLVL-------STLFMGGHLMSTESLSPGALMAFLV 406
               |:....|.|.|   .|..|.|...|.||.|       ..::.||.|:..:..:.|.::..::
plant   270 ---NKHLVTAYKAG---VIEGGSTGLGLGTLFLVVFCSYALAVWYGGKLILDKGYTGGQVLNIII 328

  Fly   407 ASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVE--LLRGYIIPQERLHGEIRFENVSF 469
            |......||.|.|..|.....|.:|..::||.:..:|.::  ...|.::  :.:.|:|..::|.|
plant   329 AVLTGSMSLGQTSPCLSAFAAGQAAAYKMFETIERRPNIDSYSTNGKVL--DDIKGDIELKDVYF 391

  Fly   470 AYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPY 534
            .||.:||..:.:.|||.:..|.||||||.|||||||:.||:||||:|.||::.:||..|.:....
plant   392 TYPARPDEQIFRGFSLFISSGTTVALVGQSGSGKSTVVSLIERFYDPQAGDVLIDGINLKEFQLK 456

  Fly   535 WLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERG 599
            |:||.: |.:.|:||||..||.:||.|||.||..|::.|||.|:.:..||..||.|..|.|||.|
plant   457 WIRSKI-GLVSQEPVLFTASIKDNIAYGKEDATTEEIKAAAELANASKFVDKLPQGLDTMVGEHG 520

  Fly   600 TQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIR 664
            |||||||:||||:|||:||:||||:||||||||||.||..||:|||.::.||||:|:||||||:|
plant   521 TQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTVVVAHRLSTVR 585

  Fly   665 NADLIVVLDQGRVVETGKHDELM-GKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQATATET 728
            |||:|.|:.||::||.|.|.||: ...|.|.:|:|.||.:...|.        |.:||:.::.|:
plant   586 NADMIAVIHQGKIVEKGSHTELLKDPEGAYSQLIRLQEEKKSDEN--------AAEEQKMSSIES 642

  Fly   729 STAATIATAAETSAATVTVGSSSFG 753
            ...:::..:  :...:::.|.||.|
plant   643 FKQSSLRKS--SLGRSLSKGGSSRG 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	220/603 (36%)
ABCB4	NP_182223.1	PTZ00265	46..1280	CDD:240339	229/653 (35%)
		MdlB	705..1285	CDD:440747