Protein Alignment CG1824 and Abcb5

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_084237.1
• Gene: Abcb5 / 77706
• MGIID: 1924956
• Length: 1255
• Species: Mus musculus
• Alignment Length: 651
• Identity: 216/651 - (33%)
• Similarity: 332/651 - (50%)
• Gaps: 110/651 - (16%)

  Fly   140 ALIVAYINIRIPNLLGDLVNT-LARYAN-TYVMDPINNSFVKDVSKPASNLLSLYMLQSG----- 197
            :|::..|:..:.|  |.||.| ..:|.| :...:.:|...:         :|:||.:..|
Mouse    67 SLVLGEISDHLIN--GCLVQTNRTKYQNCSQTQEKLNEDII---------VLTLYYIGIGAAALI 120

  Fly   198 FTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQ 262
            |.::.|........:...::|:..|..|:.|||::||.:...||..|:|.|:..        :..
Mouse   121 FGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINK--------LCD 177

  Fly   263 GLRSAAQLIGGSISLFMI--------SPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAER 319
            |:.....|:..:||.|.|        |..::.:.|::.|.::.......:.:.||:........:
Mouse   178 GIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSK 242

  Fly   320 ATGVCEEALSNIRTVRSSACEYREMQLFEAETNEA------ARLAQKL-----------GYGIAI 367
            |..|.|||||:|:||.:...:.:|:|.:.....:|      ...|.||           .||:|.
Mouse   243 AGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAF 307

  Fly   368 FQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLG--------- 423
            :.|           ::|..||        .||..:..::|   |..|:...|..:|
Mouse   308 WYG-----------TSLIFGG--------EPGYTIGTILA---VFFSVIHSSYCIGSVAPHLETF 350

  Fly   424 TMIRGMSAGSRVFEFLSLQPQVE--LLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLT 486
            |:.||  |...:|:.:..:|.::  ...|::  .|.:.|.|.|:||||:||.:|...|||..:|.
Mouse   351 TVARG--AAFNIFQVIDKKPNIDNFSTAGFV--PECIEGNIEFKNVSFSYPSRPSAKVLKGLNLK 411

  Fly   487 LRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLR--SNVLGFIEQQPV 549
            ::.|:||||||.|||||||...|::|.|:|..|.|.:|.   :||....:|  ...:|.:.|:||
Mouse   412 IKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDE---NDIRAQNVRHYREQIGVVRQEPV 473

  Fly   550 LFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIAR 614
            ||||:|..||::|:...||:::..|||.:.::||:.|.|..:.|.|||:|.|:||||:|||||||
Mouse   474 LFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIAR 538

  Fly   615 ALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVE 679
            ||::||:||||||||||||..||:.||.||:...:.|||:|:||||||||.|||||.:..|.|||
Mouse   539 ALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVE 603

  Fly   680 TGKHDELMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQATATETSTAATIATAAETSAAT 744
            .|.|.|||.|:|||:.|...|:.:.:.||:                 |:.|.:|...|:..|...
Mouse   604 KGTHAELMAKQGLYYSLAMAQDIKKVDEQM-----------------ESRTCSTAGNASYGSLCD 651

  Fly   745 V 745
            |
Mouse   652 V 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	208/606 (34%)
Abcb5	NP_084237.1	PTZ00265	48..1250	CDD:240339	216/651 (33%)
		MdlB	48..624	CDD:440747	207/604 (34%)