DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1824 and tap2t

DIOPT Version :9

Sequence 1:	NP_572810.1	Gene:	CG1824 / 32208	FlyBaseID:	FBgn0030403	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	XP_005156356.1	Gene:	tap2t / 556826	ZFINID:	ZDB-GENE-130531-48	Length:	728	Species:	Danio rerio

Alignment Length:	700	Identity:	226/700 - (32%)
Similarity:	349/700 - (49%)	Gaps:	89/700 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LRGTN-APQPPAIPPTNASRLLQTTRLLVW------GGGSLAIGLGARSWWAGHRGAIVHCEGSR 99
            |||.| .|.|..:..::|:.:|   ..:||      ||.|    .|.|:
Zfish   101 LRGFNPVPDPGMVILSSATSIL---IYMVWEMAFPHGGSS----KGGRN---------------- 142

  Fly   100 LAIRKEEEEEDTASEQHFDWKRLWTYLEPHLWELIGAVCAALIVAYINIRIPNLLGDLVNTLARY 164
               :|::||......:...:.|| .||      .:||       |:|.:.    |..|..|...|
Zfish   143 ---QKKDEEARALLMRVIRYSRL-DYL------YLGA-------AFIFLS----LAALFETFIPY 186

  Fly   165 ANTYVMDPINNSFVKDVSKPASNLLSLYMLQSGFTF-----MYIYLLSRVGEQMAAKMRQDLFTQ 224
            ....|:|.::..:.......|..||:|..|.|....     |:::.|:|:.:    ::|..||..
Zfish   187 CTGKVIDILSGKYQHSNFTWAILLLALCSLGSSMFSGLRGGMFMFSLNRLNK----RIRNLLFQN 247

  Fly   225 IVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHMAAIAL 289
            ::.|:|.||||.:.|.|.:||.:|......:....|:..|||..:..|  :..||:.   .:..|
Zfish   248 VMKQEIDFFDEIKPGNLASRLISDTDKMGRAVAMNVNVLLRSMVKTCG--MLYFMLG---VSWQL 307

  Fly   290 ASVPCVVM-FMTYLGKKLRSLSKSSQAQAE---RATG-VCEEALSNIRTVRSSACEYREMQLFEA 349
            ..:.|:.| .:.:|.....|||:.:..:.:   ..|| :....:.:|:||||...|.:|.|.:|.
Zfish   308 TLLTCIEMPLLAFLQNSYNSLSQKTSKELQDCNAETGELASSVIGSIKTVRSFKAECQEQQRYEQ 372

  Fly   350 ETNEAARLAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRS 414
            ..|...::.::.|:..|::..:..|....|.::.|..|.:|:|:..||.|:|:||:...:.:..|
Zfish   373 TINRKLQVLRRKGFYSAVYLLIRRFITVGLKVAMLCQGRNLISSGQLSSGSLLAFVFYQKDMVTS 437

  Fly   415 LAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLV 479
            :.....:.|.|:..:.:..:||:.|..:||:. ..|.:.| |:|.|.|.||.|:|:|..:||...
Zfish   438 MKHLVYIYGDMLSTVGSSVKVFQLLDRKPQMR-EAGDLAP-EKLKGRITFEKVTFSYLSRPDDTA 500

  Fly   480 LKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFI 544
            ||..:|.|.||:..||||.||.|||:..||::|||||..|.:.|||..|......:|...| ..:
Zfish   501 LKSVTLELSPGKLTALVGPSGGGKSSCVSLLQRFYEPKEGEMFLDGEPLYHYQHQYLHKKV-AVV 564

  Fly   545 EQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQR 609
            .|.||||..|:..||.||..|...|.:..|||.:.:|:|:..|..||.|.|||.|.|||.||:|.
Zfish   565 SQDPVLFSGSVRYNIEYGLQDCTLERIEEAARKANAHNFICNLEQGYDTDVGECGGQLSAGQKQC 629

  Fly   610 IAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQ 674
            |||||||::||:|||||||||.:|::::..:|..|:::. ::|.|||||||.||..||.|:.::.
Zfish   630 IAIARALIRNPQILILDEATSHMDSSTQQAIQDVLNSIT-DQTVLVIAHRLETIEKADHIIFMEG 693

  Fly   675 GRVVETGKHDELMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQAT 724
            |.|.|.|.|.:||.|:|.|..|               .|.:..::.||||
Zfish   694 GEVKEQGTHQQLMDKQGRYHRL---------------REKLFNLETQQAT 728

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..701	CDD:224055	203/591 (34%)
		ABC_membrane	137..415	CDD:279056	71/287 (25%)
		ABC_MTABC3_MDL1_MDL2	462..700	CDD:213216	113/237 (48%)
tap2t	XP_005156356.1	SunT	28..715	CDD:331423	220/670 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0058
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D684058at2759
OrthoFinder	1	1.000	-	-		FOG0000243
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820