Protein Alignment CG1824 and Hmt-1

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_650503.1
• Gene: Hmt-1 / 41925
• FlyBaseID: FBgn0038376
• Length: 866
• Species: Drosophila melanogaster
• Alignment Length: 821
• Identity: 223/821 - (27%)
• Similarity: 353/821 - (42%)
• Gaps: 195/821 - (23%)

  Fly    49 QPPAIPPTNASRLLQTTRLLVWG----GGSLA-IGLGARSWWAGHRGAIVHCEGSRLAIR----- 103
            |.|::|......:|    ||.|.    ..||| |.|....||       .|.:.::..|.
  Fly   125 QLPSMPTRGHGLVL----LLFWTLAFINESLAFINLRHEDWW-------FHLKTNKDQIEMGLFV 178

  Fly   104 -------------------------KEEEEEDTASEQHFD----------WKRLWTYLEPHLW-- 131
                                     .:..:.|||:|...:          |::|.|.. |:||
  Fly   179 TRFLCSLLIFVLGLKAPGIMAPYNPHQRLDNDTANESQGNVQTGSAFRNGWRKLRTVF-PYLWPK 242

  Fly   132 -----ELIGAVCAALIVA--YINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDVSKPASNLL 189
                 ::...||..|::|  .|.:.:|.....||::|......:..|     ||       ...:
  Fly   243 KNIALQIAVIVCIILLLAGRVIKLFLPIYRKKLVDSLTIAPIVFRWD-----FV-------LIYV 295

  Fly   190 SLYMLQSG-------FTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTA 247
            :|..||.|       |..:..:|..||.:....::..:||..:....:.:..:.:|||::
  Fly   296 ALSFLQGGGTGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVL----- 355

  Fly   248 DVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYLG--------- 303
                      :.:.:|..|...|:  :..:|.|:|.:..:.:|....|..|..:.|
  Fly   356 ----------RVMDRGTDSINNLL--NYIVFSIAPTILDLLVAVAYFVYAFNWWFGLIVFLTMFL 408

  Fly   304 -------------KKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAA 355
                         |..|.::.:...|..|:.    ::|.|..||:....|:.|:..:    .||.
  Fly   409 YIASTIAITEWRTKYQRRMNLADNEQRARSV----DSLLNFETVKYYGAEHYEVDCY----REAI 465

  Fly   356 RLAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALM-AFLVASQGVQRSLAQGS 419
            ...||            ..||:.|.|:.|....:::....|..|:|: .:||..   .::|..|.
  Fly   466 LKYQK------------EEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVH---HQTLTVGD 515

  Fly   420 ILL---------------GTMIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERL----------- 458
            .:|               ||..|.:..     .|:.::...:||:    .:|.:
  Fly   516 FVLFSTYLMELYMPLNWFGTYYRAIQK-----NFVDMENMFDLLK----EEEEIVDAPGCSPLLT 571

  Fly   459 -HGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIK 522
             .|.|.|.||:|.|  .|:.:||::.|.|:..|:|||:||.||:|||||..|:.|||:...|.|.
  Fly   572 AGGGIEFSNVTFGY--SPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAIL 634

  Fly   523 LDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTAL 587
            :||..:..:....|| ..:|.:.|..|||..:|..||.|.|..|.:|.||.|||.:..|:.:...
  Fly   635 IDGQNIKLVQQQSLR-KAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGF 698

  Fly   588 PDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRT 652
            |:.|.|.|||||.:||||::||:||||.|||.|.|::|||||||||..:|..:|.||..|..|||
  Fly   699 PEKYETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANRT 763

  Fly   653 TLVIAHRLSTIRNADLIVVLDQGRVVETGKHDEL-MGKRGLYFELVRQQERRDIQEQVQAVEDVV 716
            |:::|||||||.:||.|:||.||.:.|.|:|:|| :.:.|:|.::.:||.:....||....::..
  Fly   764 TIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGIYADMWQQQLKNLDAEQSGGSDNGD 828

  Fly   717 AVKEQQATATETSTAATIATAAETSAATVTVGSSSFGGRAN 757
            |       :.|:.:....|..|...:.|.|.|:....|.|:
  Fly   829 A-------SAESGSEKRRAGGAGGPSGTGTGGAHFRAGHAH 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	192/649 (30%)
Hmt-1	NP_650503.1	MTABC_N	3..241	CDD:465049	25/127 (20%)
		ATM1	222..821	CDD:444078	193/663 (29%)