Protein Alignment CG1824 and Mdr65

DIOPT Version :9

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Alignment Length: 604
• Identity: 209/604 - (34%)
• Similarity: 326/604 - (53%)
• Gaps: 54/604 - (8%)

  Fly   174 NNSFVKDVSKPASNLL---SLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFD- 234
            ||..:.|.|.....||   |:.|..||...:.::  :.|..:...:||..||:.::.|||.:.|
  Fly   109 NNEALYDDSISYGILLTIASVVMFISGIFSVDVF--NMVALRQVTRMRIKLFSSVIRQDIGWHDL 171

  Fly   235 ---ENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMIS---PHMAAIALAS-V 292
               :|.|..:|:    ||:..:..    :|:.:.....|:.|.|....||   .....:|::| :
  Fly   172 ASKQNFTQSMVD----DVEKIRDG----ISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYI 228

  Fly   293 PCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARL 357
            |.|::...|:.|....|:...|.....|..:.||.||:||||.|...|..|:|.:|.....|.:.
  Fly   229 PLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKA 293

  Fly   358 AQKLGYGIAIFQGLTNFFLNT-LVLS---------TLFMGGHLMSTESLSPGALM-AFLVASQGV 411
            :|..|    .|.||::..|.: |.||         .|.:....:..:..:|..|| ||.....|.
  Fly   294 SQWKG----AFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGA 354

  Fly   412 QRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLR--GYIIPQERLHGEIRFENVSFAYPMQ 474
            . ::|:.:..|.:........:.:|:.:.|..:::.|.  |.:: ...|.|::.|::|.|.||.:
  Fly   355 D-NIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLL-NYGLRGDVEFQDVFFRYPSR 417

  Fly   475 PDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSN 539
            |:.:|.:..::.:|.||||||||:||.||||...|::|||:|..|::.||...:...:..|||||
  Fly   418 PEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSN 482

  Fly   540 VLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSG 604
            : ..:.|:||||..:|.:||.||||.|.::::.|||..:.:|:|:|.||:.|.:.:||||:||||
  Fly   483 I-AVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSG 546

  Fly   605 GQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLI 669
            ||:|||||||||::||:||:|||||||||..||.:||:|||...:.|||:|::||||.||.||.|
  Fly   547 GQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKI 611

  Fly   670 VVLDQGRVVETGKHDELMGKRGLYFELVRQQE--RRDIQEQVQAVEDVVAVKEQQATATETSTAA 732
            |.:..|:|:|.|.||:||...|.|:.:||..:  ..|..|:..::||           |:..:.|
  Fly   612 VFIHDGKVLEEGSHDDLMALEGAYYNMVRAGDINMPDEVEKEDSIED-----------TKQKSLA 665

  Fly   733 TIATAAETSAATVTVGSSS 751
            ....:.|||......|..:
  Fly   666 LFEKSFETSPLNFEKGQKN 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..701	CDD:224055	199/550 (36%)
		ABC_membrane	137..415	CDD:279056	69/262 (26%)
		ABC_MTABC3_MDL1_MDL2	462..700	CDD:213216	122/237 (51%)
Mdr65	NP_476831.1	PTZ00265	91..1300	CDD:240339	209/604 (35%)
		ABC_membrane	108..354	CDD:279056	68/258 (26%)
		ABC_MTABC3_MDL1_MDL2	405..642	CDD:213216	122/237 (51%)
		ABC_membrane	736..1006	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1059..1299	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I220
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51436
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	P	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.910