Protein Alignment CG1824 and Mdr50

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_523740.3
• Gene: Mdr50 / 36582
• FlyBaseID: FBgn0010241
• Length: 1313
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 218/694 - (31%)
• Similarity: 340/694 - (48%)
• Gaps: 110/694 - (15%)

  Fly   105 EEEEEDTASEQHFDWK-----RLWTYLEP-----HLWELIGAVCAALIVAYINIRIPNLLGDLVN 159
            :..:|:..|:.|.|.|     :|:.|...     ::..|:.||...|.....::...||..|:::
  Fly    54 DASDEEDGSQYHEDVKQVSYFQLFRYATKKDRALYVIGLLSAVATGLTTPANSLIFGNLANDMID 118

  Fly   160 T--LARYANTYVMDPINNSFVKDVSKPAS---NLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQ 219
            .  |.....:|..|...::.:.|..:..|   ..:.:.||..  :::.|...:.........:|.
  Fly   119 LGGLLESGKSYRADDAISTLLLDKVRQFSLQNTYIGIIMLVC--SYLSITCFNYAAHSQILTIRS 181

  Fly   220 DLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHM 284
            ..|..|:.||:.::|.|::||:.:|:..|:...:....:.|...:......:|..:..|:....:
  Fly   182 KFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQL 246

  Fly   285 AAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEA 349
            :.:.|.|:|...:.|..:......|:|........|..|.|.|||.||||::          ||.
  Fly   247 SLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGALSGIRTVKA----------FEG 301

  Fly   350 ETNEAARLAQK----------------LGYGIAIFQGLTNFFLNTLVLS------TLFMGGHLMS 392
            |..|.|...::                :|:|:..|     |...:..|:      .:..|.|..:
  Fly   302 EAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWF-----FIYASYALAFWYGVGLVIKGYHEPA 361

  Fly   393 TESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAG------------SRVFEFLSLQPQV 445
            .|:...|.::....            |:::|:|..||:|.            ::||..:...|::
  Fly   362 YENYDAGTMITVFF------------SVMMGSMNIGMAAPYIEAFGIAKGACAKVFHIIEQIPEI 414

  Fly   446 ELLRGYIIPQERLH---GEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIA 507
            ..:.|   ..::|:   ..|.|:.|.|.||.:|:..:|...:|.:..||||||||.||.||||..
  Fly   415 NPIDG---EGKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLKIHRGQTVALVGPSGCGKSTCI 476

  Fly   508 SLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVY 572
            .||:|||:|.|||:..:|..|.|:...||||.: |.:.|:|:||.|||.||||||:.||..|::.
  Fly   477 QLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRI-GVVGQEPILFATSIYENIRYGREDATREEIE 540

  Fly   573 AAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSE 637
            |||..:.:..|:..||.||.|.|||||.||||||:|||||||||:::|.||:|||||||||..||
  Fly   541 AAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATSALDTASE 605

  Fly   638 AEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLYFELVRQQ-- 700
            |:||.||:.|...|||:::||||||:|.||.|||:::|.|||:|.|.|||..:..||.||..|
  Fly   606 AKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQELMELKDHYFNLVTTQLG 670

  Fly   701 --------------ERRDI----QEQVQAV-----EDVVAVKEQ 721
                          :..||    :|:::.:     |||:...|:
  Fly   671 EDDGSVLSPTGDIYKNFDIKDEDEEEIKVLSEDEDEDVMVTDEK 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	207/650 (32%)
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	214/679 (32%)