Protein Alignment CG1824 and Abcc2

DIOPT Version :9

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_036965.1
• Gene: Abcc2 / 25303
• RGDID: 2366
• Length: 1541
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 151/551 - (27%)
• Similarity: 259/551 - (47%)
• Gaps: 94/551 - (17%)

  Fly   186 SNLLSLYMLQSGFTFMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQ 250
            |.|.|:|..::....::..||:.:   :.|.||             |||...||.:|||.:.|:
  Rat  1037 STLWSIYACRNASKALHGQLLTNI---LRAPMR-------------FFDTTPTGRIVNRFSGDI- 1084

  Fly   251 DFKTSFKQFVSQGLRSAAQ-LIGGSISLFMISPHMAAIALASVPCVVMFMT----YLG-----KK 305
               ::....:.|.|||... ..|.:.:|.||.......|:..:|..:::::    |:.     ::
  Rat  1085 ---STVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRR 1146

  Fly   306 LRSLSKSS--QAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLGYGIAIF 368
            |.|::||.  ...:|..||     |..||.       :...|.|.|...:...:.||     .:|
  Rat  1147 LDSVTKSPIYSHFSETVTG-----LPIIRA-------FEHQQRFLAWNEKQIDINQK-----CVF 1194

  Fly   369 QGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSIL------------ 421
            ..:|:   |..:...|.:.|:|:...|       |.|:.   :.|....|.::
  Rat  1195 SWITS---NRWLAIRLELVGNLVVFCS-------ALLLV---IYRKTLTGDVVGFVLSNALNITQ 1246

  Fly   422 -LGTMIRGMS-------AGSRVFEFLSLQPQVELLRGYIIPQE-RLHGEIRFENVSFAYPMQPDH 477
             |..::|..|       |..|:.|:::::.:...:.....|.: ..||||:|.|....|..:.|
  Rat  1247 TLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDKRPPADWPRHGEIQFNNYQVRYRPELD- 1310

  Fly   478 LVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLG 542
            ||||..:..::.|:.|.:||.:|:|||::.:.:.|..|.:.|.|.:||..::.|..:.||.. |.
  Rat  1311 LVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRER-LT 1374

  Fly   543 FIEQQPVLFGTSILENI----RYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLS 603
            .|.|.|:||..|:..|:    :|     .:|:|:.|..|:....||:.|..|..:.|.|.|..||
  Rat  1375 IIPQDPILFSGSLRMNLDPFNKY-----SDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLS 1434

  Fly   604 GGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADL 668
            .||||.:.:.||:|:..:||:|||||:|:|..:::.:|..:.......|.:.|||||.||.::|.
  Rat  1435 IGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDK 1499

  Fly   669 IVVLDQGRVVETGKHDELMGKRGLYFELVRQ 699
            |:|||.|::||.|..:||:..||.::.:.::
  Rat  1500 IMVLDNGKIVEYGSPEELLSNRGSFYLMAKE 1530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..701	CDD:224055	151/551 (27%)
		ABC_membrane	137..415	CDD:279056	54/240 (23%)
		ABC_MTABC3_MDL1_MDL2	462..700	CDD:213216	86/242 (36%)
Abcc2	NP_036965.1	MRP_assoc_pro	7..1533	CDD:188098	151/551 (27%)
		ABC_membrane	322..589	CDD:279056
		ABCC_MRP_domain1	633..834	CDD:213217
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	862..881
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	901..923
		ABC_membrane	979..1245	CDD:279056	55/257 (21%)
		ABCC_MRP_domain2	1294..1514	CDD:213211	84/226 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000