Protein Alignment CG1824 and Abcb4

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_036822.1
• Gene: Abcb4 / 24891
• RGDID: 620248
• Length: 1278
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 210/636 - (33%)
• Similarity: 317/636 - (49%)
• Gaps: 86/636 - (13%)

  Fly   152 NLLGDLVNTLARYAN------------------------TYVMDPINNSFVKDV---SKPASNLL 189
            ||:|.|  ||.||::                        ..|...:.:.||.:.   |.|.:  .
  Rat    35 NLIGPL--TLFRYSDWQDKLFMLLGTAMAIAHGSGLPLMMIVFGEMTDKFVDNAGNFSLPVN--F 95

  Fly   190 SLYMLQSGFTF-----MYIYLLSRVGE-------------QMAA-----KMRQDLFTQIVVQDIA 231
            ||.||..|...     .|.|..|.:|.             .:||     |:||..|..|:.|::.
  Rat    96 SLSMLNPGRILEEEMTRYAYYYSGLGGGVLLAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEMG 160

  Fly   232 FFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHMAAIALASVPCVV 296
            :||...|.||..|||.|:..........|....::.|....|.|..|:....:..:.:|....:.
  Rat   161 WFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAITAILG 225

  Fly   297 MFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQK- 360
            :......|.|.:.|....|...:|..|.||||..||||.:...:.:|::.::.....|.::..|
  Rat   226 LSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKK 290

  Fly   361 -----LGYGIAIF-----QGLTNFFLNTLVLSTLFMGGHLMST-ESLSPGALMAFLVASQGVQRS 414
                 :..|||..     ..|..::.:|||:|..:..|:.|:. .|:..||.            |
  Rat   291 AISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAF------------S 343

  Fly   415 LAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELL--RGYIIPQERLHGEIRFENVSFAYPMQPDH 477
            :.|.:..:........|...:|:.:...|:::..  ||:  ..:.:.|.:.|.:|.|:||.:.:.
  Rat   344 VGQAAPCIDAFPNARGAAYVIFDIIDNNPKIDSFSERGH--KPDSIKGNLEFSDVHFSYPSRANI 406

  Fly   478 LVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLG 542
            .:||..:|.::.||||||||.||.||||...|::|.|:|:.|.|.:||..:.:.:...|| ..:|
  Rat   407 KILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGTISIDGQDIRNFNVRCLR-EFIG 470

  Fly   543 FIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQR 607
            .:.|:||||.|:|.||||||:.:...:::..|.:.:.::||:..||..:.|.||:||.||||||:
  Rat   471 VVSQEPVLFSTTIAENIRYGRGNVTMDEIKKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQK 535

  Fly   608 QRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVL 672
            |||||||||::||:||:|||||||||..||||||.|||...:.|||:||||||||:||||:|...
  Rat   536 QRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGF 600

  Fly   673 DQGRVVETGKHDELMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQA 723
            :.|.:||.|.|.||:.|.|:||.||..|..   ..|:.:.|..|.:.:::|
  Rat   601 EDGVIVEQGSHSELIKKEGIYFRLVNMQTS---GSQILSEEFEVELSDEKA 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	206/613 (34%)
Abcb4	NP_036822.1	PTZ00265	29..1271	CDD:240339	210/636 (33%)
		MdlB	42..632	CDD:440747	201/609 (33%)
		Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385	622..646		7/26 (27%)