Protein Alignment CG1824 and Tap2

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_114445.2
• Gene: Tap2 / 24812
• RGDID: 3818
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 205/648 - (31%)
• Similarity: 347/648 - (53%)
• Gaps: 63/648 - (9%)

  Fly    70 WG---GGSLAIGLGARSWWAGHRGAIVHCEGSRLAIRKEEEEEDTASEQHFDWKRLWTYLEPHLW 131
            ||   .|.:|..|....|      |::...|::   .||..:|:..:..    .||....:|.|
  Rat    99 WGWLLAGYVAAALSLAVW------AVLSPAGAQ---EKEPGQENNRALM----IRLLRLSKPDL- 149

  Fly   132 ELIGAVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDVSKPASNLLSLYMLQS 196
                   ..||||:|.:.:. :.|:   ||..:.:..|:|.:...|..|....|...:.|:.:.|
  Rat   150 -------PFLIVAFIFLAMA-VWGE---TLIPHYSGRVIDILGGDFDPDAFASAIFFMCLFSVGS 203

  Fly   197 GFTF-----MYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSF 256
            ..:.     .:::.:||:.    .::|:.||:.::.||:|||.|.:||||.:||::|........
  Rat   204 SLSAGCRGGSFLFTMSRIN----LRIREQLFSSLLRQDLAFFQETKTGELNSRLSSDTSLMSRWL 264

  Fly   257 KQFVSQGLRSAAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERAT 321
            ....:..|||..:::|....:..:||.:..::|..:|..:........:.:::.|..|....:|.
  Rat   265 PFNANILLRSLVKVVGLYYFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDVVAKAG 329

  Fly   322 GVCEEALSNIRTVRSSACEYREMQLFEAETNEAAR-------LAQKLGYGIAIFQGLTNFFLNTL 379
            .|..||:..::||||...|.:|:..:: |..|..|       |.::|   ..:.:.:....:..|
  Rat   330 QVVREAVGGLQTVRSFGAEEQEVSRYK-EALERCRQLWWRRDLEKEL---YLVIRRVMALGMQVL 390

  Fly   380 VLSTLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQ 444
            :|:   .|...:....::.|.|::||:..:.|...:.....:.|.|:..:.|..:||.:|..:|.
  Rat   391 ILN---CGVQQILAGEVTRGGLLSFLLYQEEVGHHVRNLVYMYGDMLSNVGAAEKVFSYLDRRPN 452

  Fly   445 VELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASL 509
            :. ..|.:.| .|:.|.:.|::|||:||.:|:..||:..:.||.||:..||||.:||||||:|:|
  Rat   453 LP-KPGTLAP-PRVEGRVEFQDVSFSYPSRPEKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAAL 515

  Fly   510 VERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAA 574
            ::..|:|:.|.:.|||..|.....::|...|: .:.|:||||..|:.:||.||..:..:..|.||
  Rat   516 LQNLYQPTGGKVLLDGEPLVQYDHHYLHRQVV-LVGQEPVLFSGSVKDNIAYGLRNCEDAQVMAA 579

  Fly   575 ARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAE 639
            |:.:.:.||:..:.:|..|.:||||:||:.||:||:||||||::|||:|||||||||||    ||
  Rat   580 AQAACADDFIGEMTNGINTEIGERGSQLAVGQKQRLAIARALVRNPRVLILDEATSALD----AE 640

  Fly   640 VQKALDT--VVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLYFELVRQQ 700
            .::||.|  ..::||.|||||||.|::|||.::||.||::||   ||:|..::.:|..||:|:
  Rat   641 CEQALQTWRSQEDRTMLVIAHRLHTVQNADQVLVLKQGQLVE---HDQLRDEQDVYAHLVQQR 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	194/596 (33%)
Tap2	NP_114445.2	3a01208	1..697	CDD:273363	202/643 (31%)