Protein Alignment CG1824 and ABCB9

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_062571.1
• Gene: ABCB9 / 23457
• HGNCID: 50
• Length: 766
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 234/667 - (35%)
• Similarity: 355/667 - (53%)
• Gaps: 77/667 - (11%)

  Fly    67 LLVWGGGSLAIGLGAR--SWW----------AGHRGAIVHCEGSRLAIRKEEEEEDTASEQHFDW 119
            |.||    ..|.|||.  .||          |...||....||...:.|...|:...|:.|
Human   119 LFVW----TYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQ---- 175

  Fly   120 KRLWTYLEPHLWELIGAVCAALIVAYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVKDVSKP 184
             :|.:|.:|.:..|:.|....::.|.....:|...|..::.:....:   ||..:.:.|
Human   176 -KLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKS---MDQFSTAVV------ 230

  Fly   185 ASNLLSLYMLQSGFT-------FMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELV 242
               ::.|..:.|.|.       |..|:      .::..::|..||..:|.|:.:||||||||:|:
Human   231 ---IVCLLAIGSSFAAGIRGGIFTLIF------ARLNIRLRNCLFRSLVSQETSFFDENRTGDLI 286

  Fly   243 NRLTADVQDFKTSFKQFVSQG----LRSAAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYLG 303
            :|||:|.    |.....|||.    ||:..::.|..:.:|.:|..::.:.....|.::|.....|
Human   287 SRLTSDT----TMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYG 347

  Fly   304 KKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLGYGIAIF 368
            |..:.|||..|....||:...||.:|.::||||.|.|..|.:::..:..:..:|.:|.......:
Human   348 KYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYY 412

  Fly   369 ---QGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLV-------ASQGVQRSLAQGSILLG 423
               .|||   |..:.:|.|:.||||:.:..::.|.|:||::       ..:.|      ||:..|
Human   413 VWGSGLT---LLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESV------GSVYSG 468

  Fly   424 TMIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLR 488
            .| :|:.|..:||||:..||.: :..|.:.| :.|.|.:.||||:|.|..:|...||::.|.:|.
Human   469 LM-QGVGAAEKVFEFIDRQPTM-VHDGSLAP-DHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLS 530

  Fly   489 PGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGT 553
            ||:..||||.||||||:..:::|.||....|.:.|||..:|.....:|. .|:..:.|:||||..
Human   531 PGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH-RVISLVSQEPVLFAR 594

  Fly   554 SILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLK 618
            ||.:||.||.|....|.|..||:.:.:|.|:..|.|||:|..||:|.||||||:||:|:||||::
Human   595 SITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVR 659

  Fly   619 NPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKH 683
            ||.:||||||||||||.||..:|:|:...:|..|.|:|||||||:.:|.||||||:||||:.|.|
Human   660 NPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTH 724

  Fly   684 DELMGKRGLYFELVRQQ 700
            .:|:.:.|||.:||::|
Human   725 QQLLAQGGLYAKLVQRQ 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	216/603 (36%)
ABCB9	NP_062571.1	3a01208	44..738	CDD:273363	231/662 (35%)