Protein Alignment CG1824 and Abcb4

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_032856.2
• Gene: Abcb4 / 18670
• MGIID: 97569
• Length: 1276
• Species: Mus musculus
• Alignment Length: 636
• Identity: 214/636 - (33%)
• Similarity: 319/636 - (50%)
• Gaps: 86/636 - (13%)

  Fly   152 NLLGDLVNTLARYAN------------------------TYVMDPINNSFVKDV---SKPASNLL 189
            ||:|.|  ||.||::                        ..|...:.:.||.:.   |.|.:  .
Mouse    35 NLIGLL--TLFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKFVDNTGNFSLPVN--F 95

  Fly   190 SLYMLQSGFTF-----MYIYLLSRVGE-------------QMAA-----KMRQDLFTQIVVQDIA 231
            ||.||..|...     .|.|..|.:|.             .:||     |:||..|..|:.|::.
Mouse    96 SLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMG 160

  Fly   232 FFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHMAAIALASVPCVV 296
            :||...|.||..|||.||..........|....::.|....|.|..|:....:..:.:|..|.:.
Mouse   161 WFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILG 225

  Fly   297 MFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQK- 360
            :......|.|.:.|....|...:|..|.||||..||||.:...:.:|::.::.....|.::..|
Mouse   226 LSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKK 290

  Fly   361 -----LGYGIAIF-----QGLTNFFLNTLVLSTLFMGGHLMST-ESLSPGALMAFLVASQGVQRS 414
                 :..|||..     ..|..::.:|||:|..:..|:.|:. .|:..||.            |
Mouse   291 AISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAF------------S 343

  Fly   415 LAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELL--RGYIIPQERLHGEIRFENVSFAYPMQPDH 477
            :.|.:..:........|...:|:.:...|:::..  ||:  ..:.:.|.:.|.:|.|:||.:.:.
Mouse   344 VGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSERGH--KPDNIKGNLEFSDVHFSYPSRANI 406

  Fly   478 LVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLG 542
            .:||..:|.::.||||||||.||.||||...|::|.|:|:.|.|.:||..:.:.:...|| .::|
Mouse   407 KILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLR-EIIG 470

  Fly   543 FIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQR 607
            .:.|:||||.|:|.||||||:.:...:::..|.:.:.::||:..||..:.|.||:||.||||||:
Mouse   471 VVSQEPVLFSTTIAENIRYGRGNVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQK 535

  Fly   608 QRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVL 672
            |||||||||::||:||:|||||||||..||||||.|||...:.|||:|||||||||||||:|...
Mouse   536 QRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGF 600

  Fly   673 DQGRVVETGKHDELMGKRGLYFELVRQQERRDIQEQVQAVEDVVAVKEQQA 723
            :.|.:||.|.|.|||.|.|:||.||..|   ....|:.:.|..|.:.:::|
Mouse   601 EDGVIVEQGSHSELMKKEGIYFRLVNMQ---TAGSQILSEEFEVELSDEKA 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	210/613 (34%)
Abcb4	NP_032856.2	PTZ00265	30..1269	CDD:240339	214/636 (34%)
		MdlB	39..632	CDD:440747	207/614 (34%)
		Interaction with HAX1. /evidence=ECO:0000250	622..646		7/26 (27%)