Protein Alignment CG1824 and pgp-12

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_510126.1
• Gene: pgp-12 / 181415
• WormBaseID: WBGene00004006
• Length: 1318
• Species: Caenorhabditis elegans
• Alignment Length: 634
• Identity: 189/634 - (29%)
• Similarity: 321/634 - (50%)
• Gaps: 64/634 - (10%)

  Fly   122 LWTYLEPHLWELIGAVCAALIVAYIN-IRIPNL---LGDLVNTLARYANTYVMDPINNSFVKDVS 182
            |:.|.|...:.|:   |..:.:::|: |..|.|   .|::.|:|.          |:|:...|..
 Worm    81 LFRYAERTDYALL---CFGIFLSFISGIAQPGLGIIAGNITNSLL----------IHNATSDDFY 132

  Fly   183 KPA-SNL-----LSLYMLQSGFT----FMYIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENR 237
            ..| :|:     :.:.:|...|.    |.|..:      ::.:||:|.....|:.|:..:||:|.
 Worm   133 DSAMTNVWLFGGIGIIVLIVNFVQYMCFQYCCI------RITSKMKQHYIQSILRQNAGWFDKNH 191

  Fly   238 TGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYL 302
            :|.|..:|..:::.........:...:|.....:.|.:..|.....:|.:.:...|...:.|:.:
 Worm   192 SGTLTTKLHDNMERINEGIGDKLGVLIRGMVMFVAGIVISFFYEWRLALMMMGIGPLCCVCMSLM 256

  Fly   303 GKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQLFEAETNEAARLAQKLGYGIAI 367
            .:.:.|.:....|...:|..:.||:|..:|||::...:...::.:..|..:....|.:.|....:
 Worm   257 SRSMSSFTSKELAGVGKAGSIAEESLMGVRTVQAFNGQEEMVEKYTVELGKGKSFAIQKGLWGGV 321

  Fly   368 FQGLTNFFLNTLVLSTLFMGGHLMSTESL-SPGALMAFLVASQGVQRSLAQGSILLG-------T 424
            |.|:...||.:.....::.||.|:..:.: :||.:...::       |:..|:..||       .
 Worm   322 FGGIFLLFLFSYFGGGIYYGGQLLRWKIIETPGDVFIVVI-------SMLIGAYFLGLISPHLMV 379

  Fly   425 MIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRP 489
            ::....|.:.::|.:...|.:::..........:.|::.||.|.|.||.:....||...:||::|
 Worm   380 LLNARVAAATIYEIIDRTPDIDVYSTEGQKMTNVVGKVVFEEVHFRYPTRKKVKVLNGLNLTVKP 444

  Fly   490 GQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTS 554
            |.:|||||.||.||||...|:.|.|||..|.:.:||..:..::..|||..| |.::|:|:||..:
 Worm   445 GTSVALVGHSGCGKSTSVGLLTRLYEPEGGKVMIDGQDVRSLNIDWLRKTV-GIVQQEPILFNDT 508

  Fly   555 ILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKN 619
            |..|:..|.|.|..||:....:::.:|||:..:|:||.|.:|:...||||||:||:||||.|:::
 Worm   509 IHNNLLIGNPSATREDMIRVCKMANAHDFIQKMPNGYETMIGDGSVQLSGGQKQRVAIARTLIRD 573

  Fly   620 PRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHD 684
            |::|:||||||||||.||:.||.||:...:.|||::|||||||||.||.||..:.|.:||:|.|:
 Worm   574 PKVLLLDEATSALDAQSESVVQSALNNAAKGRTTIMIAHRLSTIREADKIVFFENGVIVESGNHE 638

  Fly   685 ELMGKRGLYFELVRQQ---ERRDIQEQVQAVEDVVAVKEQQATATETST 730
            ||:...|.|.:||..|   |..||::.....|:            ||||
 Worm   639 ELVALGGRYAKLVEAQKFKESDDIEDNGDEHEE------------ETST 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	181/604 (30%)
pgp-12	NP_510126.1	MdlB	77..654	CDD:440747	180/599 (30%)
		PTZ00265	145..1312	CDD:240339	172/557 (31%)