Protein Alignment CG1824 and pgp-1

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_502413.1
• Gene: pgp-1 / 178215
• WormBaseID: WBGene00003995
• Length: 1321
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 220/644 - (34%)
• Similarity: 336/644 - (52%)
• Gaps: 70/644 - (10%)

  Fly   144 AYINIRIPNLLGDLVNTLARYANTYVMDPINNSFVK-DVSKPASNLLSLY------MLQSGFTFM 201
            |:||.:|      ::|   ...:|::  |...::.| |......|::..|      |..:|...:
 Worm   104 AFINEQI------VIN---NNGSTFL--PTGQNYTKTDFEHDVMNVVWSYAAMTVGMWAAGQITV 157

  Fly   202 YIYLLSRVGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRS 266
            ..||.  |.|||..::|::....|:.|:|::||.|.:|.|..:|..:::..|......:....:.
 Worm   158 TCYLY--VAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQY 220

  Fly   267 AAQLIGGSISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNI 331
            .:|.|.|.|..|..|..:..:.||..|...:....:.|.:.:.:.....:..:|..|.||.:|:|
 Worm   221 LSQFITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSI 285

  Fly   332 RTVRS-SACEYREMQLFEAETNEAARLAQKLGYGIAIFQGL-------TNFFLNTLVLSTLFMGG 388
            |||.| :...| |::.:.....|    |:|.|....:|.|:       :||....|   ..::|.
 Worm   286 RTVVSLNGLRY-ELERYSTAVEE----AKKAGVLKGLFLGISFGAMQASNFISFAL---AFYIGV 342

  Fly   389 HLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMS------------AGSRVFEFLSL 441
            ..:...||:.|.::...            .|:::|:|..|::            |.|.::|.|..
 Worm   343 GWVHDGSLNFGDMLTTF------------SSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDR 395

  Fly   442 QPQVELLRGYIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTI 506
            :|.::..........::.|:|..|||.|.||.:||..:|:..:|.:..||||||||:||.|||||
 Worm   396 KPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALVGSSGCGKSTI 460

  Fly   507 ASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDV 571
            .||:.|:|:...|.|.:||..:.||:..:||.|| ..:.|:|.||..:|.|||..||.....|::
 Worm   461 ISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNV-AVVSQEPALFNCTIEENISLGKEGITREEM 524

  Fly   572 YAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATS 636
            .||.:::.:..|:..||:||.|.||:|||||||||:|||||||||::||:||:||||||||||.|
 Worm   525 VAACKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAES 589

  Fly   637 EAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLYFELVRQQE 701
            |..||:|||...:.|||::||||||||||||||:....|:|||.|.|..||.::|||::||..|.
 Worm   590 EGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLVTAQT 654

  Fly   702 RRDIQEQVQAVEDVVAVK--EQQATATETSTAATIA-TAAETSAATVTVGSSSFGGRAN 757
            ..|      ||:.....|  .:.:.|.:||....:: .|:|.......|.||:.|...|
 Worm   655 FTD------AVDSAAEGKFSRENSVARQTSEHEGLSRQASEMDDIMNRVRSSTIGSITN 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	206/584 (35%)
pgp-1	NP_502413.1	MdlB	131..653	CDD:440747	196/544 (36%)
		MdlB	733..1319	CDD:440747