Protein Alignment CG1824 and hmt-1

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001022812.1
• Gene: hmt-1 / 176540
• WormBaseID: WBGene00001815
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 184/667 - (27%)
• Similarity: 319/667 - (47%)
• Gaps: 139/667 - (20%)

  Fly   113 SEQHFDW----KRLWTYLEPHLW-------ELIGAVCAALIVAYINIRIPNLLGDLVNTLARYAN 166
            |.:...|    |::.| :.|::|       :|....|..|::          :|.|:|......:
 Worm   195 SSRESAWNNLSKKVVT-VAPYIWPTKSISLQLRVVFCLFLLI----------IGRLINVSLPILS 248

  Fly   167 TYVMDPINNSFVKDVSKPASNLLSLYMLQSGFTFMY-------------IYLLSRVGEQMAAKMR 218
            .:::|        :::.|.:...||..|.:...|:.             .||...:.:....::.
 Worm   249 KWIVD--------ELATPDTFQYSLLFLATFLKFLQGNGAMGGFLNTVRTYLWIPIQQYTTRELE 305

  Fly   219 QDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMISPH 283
            .:||..:....:.:....:||:::               :.:.:|..|...::  :..||.:.|.
 Worm   306 VELFKHLHSLSLRWHLSRKTGQVL---------------RVMDRGTSSVNNIL--NYILFNVVPT 353

  Fly   284 MAAIALASVPCVVMFMTYLG----------------------KKLRSLSKSSQAQAERATGVCEE 326
            :|.|.:|.:.....|..|.|                      :.:|..::...|.:..||    :
 Worm   354 IADIVIAVIFFFSAFNAYFGLIVFGTMALYLTVTISITEWRTQYIREANEKDNATSAIAT----D 414

  Fly   327 ALSNIRTVRSSACEYREMQLFE--------AETNEAARLA-----QKLGYGIAIFQGLTNFFLNT 378
            :|.|..||:....|..|:..|:        .|....|.||     |....||.:..|  :.|:..
 Worm   415 SLINYETVKYYGNEEFEVNRFKNAIESYQVTEWKTQASLAFLNCLQNAIIGIGMIGG--SVFVVY 477

  Fly   379 LVL--STLFMGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAG----SRVFE 437
            :::  .||.:|.:::.|..|    |..:...:            ..||:.|.:...    ..:|:
 Worm   478 MIVHEKTLTVGDYVLFTTYL----LQLYTPLN------------FFGTIYRVIQKAFVDMENMFD 526

  Fly   438 FLSLQPQVELLRGYIIPQERLHGEIRFENVSFAY----PMQPDHLVLKDFSLTLRPGQTVALVGA 498
            .::.:.:|:.| .:.:|.....|.|..:|::|.|    |      |:|:.|..:..||||||||:
 Worm   527 LMNDEVEVKDL-PHALPYTDPRGTISVKNLTFEYNTGLP------VIKNISFEIGNGQTVALVGS 584

  Fly   499 SGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGK 563
            |||||||:..|:.|.:|.:.|:|:.||..:.:.:.:.||..: |.:.|..|||..:|:.|||:|:
 Worm   585 SGSGKSTLIRLLFRLFESTEGSIEFDGIDVRNYTMHSLRQQI-GIVPQDTVLFNDTIMYNIRFGR 648

  Fly   564 PDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEA 628
            |||.:|:|..||:.:..|:.:|:||:||||.|||||.:||||::||:||||.:||.|:.:.||||
 Worm   649 PDASDEEVIEAAKAAMIHEKITSLPEGYATMVGERGLKLSGGEKQRVAIARTILKKPQFIFLDEA 713

  Fly   629 TSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLY 693
            |||||..:|..:||.|:.:.::||.:|:||||||:.|||||:|||:|.::|.|.|.||:.::|.|
 Worm   714 TSALDTPTERAIQKCLEKLCKSRTGVVVAHRLSTVVNADLILVLDKGIILERGNHKELLAQQGTY 778

  Fly   694 FEL----VRQQERRDIQ 706
            ..:    :.:|..:.|:
 Worm   779 ASMWEAQIAEQRAKSIE 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	182/655 (28%)
hmt-1	NP_001022812.1	ATM1	213..791	CDD:444078	179/642 (28%)