Protein Alignment CG1824 and Mdr49

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_061504490.1
• Gene: Mdr49 / 1276325
• VectorBaseID: AGAMI1_004587
• Length: 1304
• Species: Anopheles gambiae
• Alignment Length: 664
• Identity: 207/664 - (31%)
• Similarity: 335/664 - (50%)
• Gaps: 71/664 - (10%)

  Fly   107 EEEDTASEQHFDWKRLWTYLEPHLWELIGAVC----AALIVAYINIRIP----------NLLGDL 157
            :|..:.|..:|...|..|:         |.||    ..|:.:..::.:|          .||.|.
Mosquito    49 KEPVSQSVSYFKLFRFATW---------GEVCVTLMGVLLASMASLGLPYGVILYGEFTTLLVDR 104

  Fly   158 VNTLARYANTYVMDPINN--------------SFVKDVSKPASNLLSLYMLQSGFTFMYIYLLSR 208
            ...:.:..:|.::.....              :.::|.......::::.:||..|..:.:.:::|
Mosquito   105 TIGIGKSTDTAILSIFGGGRVLVNATEQENAAAIMEDAKAFGLGVVAVTILQFIFATLSVDVINR 169

  Fly   209 VGEQMAAKMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGG 273
            ..::..:::||.....::.||:.::|.|.......|:|.|:...|....:.:|.........:..
Mosquito   170 SAQKQISRIRQLFLKAVLRQDMTWYDLNSDDSFAVRITDDLDKLKEGIGEKLSIFTYLVMSFVIS 234

  Fly   274 SISLFMISPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTV---- 334
            .|..|.....:..:.|:..|.:::...::.|...:|::........|..|.||.|.:||||
Mosquito   235 VIFSFFYGWKLTLVILSCAPIIILATAFVAKMQSTLTEKELKSYSSAGAVAEEVLGSIRTVVAFG 299

  Fly   335 --RSSACEYREMQLFEAETNEAAR-LAQKLG-----------YGIAIFQGLTNFFLNTLVLSTLF 385
              :..|..||| :|..||.|...: |...:|           |.:|.:.|:           :|.
Mosquito   300 GEKKEADRYRE-RLAGAELNGRRKGLFSGIGGGIMWFIIYCCYALAFWYGI-----------SLI 352

  Fly   386 MGGHLMSTESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLRG 450
            :.......:..:|..|:..|.......::|...|..|........:.:.:|..:...|.::.|..
Mosquito   353 LEDRDKDLKDYTPAVLIIVLFGVLAGAQNLGLSSPHLEAFSTAKGSAATIFSVIDRIPVIDSLGD 417

  Fly   451 YIIPQERLHGEIRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYE 515
            ..:....:.|.|:|.||.|.||.:.|..||:..:|.::.||||||||.||.||||...|::|.|:
Mosquito   418 AGLRPGSMQGNIKFSNVFFRYPARNDVQVLQGLNLEIKTGQTVALVGPSGCGKSTCLQLIQRLYD 482

  Fly   516 PSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQS 580
            |.:|::.:||.|:|:::..|||| .:|.:.|:||||.|:|.||||||.|||.:.::..||:::..
Mosquito   483 PLSGSVTIDGTKVSELNIGWLRS-FIGLVGQEPVLFATTIAENIRYGNPDASQSEIERAAKIANC 546

  Fly   581 HDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALD 645
            |.|:|.||:||.|.:||||.||||||:|||||||||::||:||:|||||||||..||..||.||:
Mosquito   547 HSFITKLPNGYGTMIGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDPNSEKRVQDALE 611

  Fly   646 TVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLYFELV---RQQERRDIQE 707
            ...:.|||||::||||||.|||.||.:|:|.|:|.|.|:|||..||||::||   ..|:..|..|
Mosquito   612 RASKGRTTLVVSHRLSTITNADKIVYIDKGLVMEQGTHEELMAARGLYYDLVVASGSQKTVDDDE 676

  Fly   708 QVQAVEDVVAVKEQ 721
            .|......::::::
Mosquito   677 SVPMAPSALSMRQE 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	201/631 (32%)
Mdr49	XP_061504490.1	None