Protein Alignment CG1824 and ABCB8

DIOPT Version :10

• Sequence 1: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001269220.1
• Gene: ABCB8 / 11194
• HGNCID: 49
• Length: 735
• Species: Homo sapiens
• Alignment Length: 680
• Identity: 333/680 - (48%)
• Similarity: 449/680 - (66%)
• Gaps: 38/680 - (5%)

  Fly    34 AARLMR--QHLRG---TNAPQPPAIPPTNASRLLQTTRLLVWGGGSLAIGLGARSWWAGHRGAIV 93
            ::.|:|  .|||.   .:.|:.|..|..:.|       ...|.||:|.             |.:|
Human    56 SSSLLRAVAHLRSQLWAHLPRAPLAPRWSPS-------AWCWVGGALL-------------GPMV 100

  Fly    94 ---HCEGSRLAIRKEEEEEDTASEQH-----FDWKRLWTYLEPHLWELIGAVCAALIVAYINIRI 150
               |.....:|:.:.||....:|..|     |:||..|.:|.|||..|..||..||..|.:|::|
Human   101 LSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQI 165

  Fly   151 PNLLGDLVNTLARYANTYVMDPINNSFVKDVSKPASNLLSLYMLQSGFTFMYIYLLSRVGEQMAA 215
            |.|||.||..:|:|...:|     .||:.:....:::||.||.:|...||.|:.|||.|||:||.
Human   166 PLLLGQLVEVVAKYTRDHV-----GSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAV 225

  Fly   216 KMRQDLFTQIVVQDIAFFDENRTGELVNRLTADVQDFKTSFKQFVSQGLRSAAQLIGGSISLFMI 280
            .||:.||:.::.|||.|||.|:||:||:|||.|||:||:|||..:||||||..|:.|..:||.|:
Human   226 DMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSML 290

  Fly   281 SPHMAAIALASVPCVVMFMTYLGKKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSACEYREMQ 345
            |..:..:.:.:.|.::...|.:|..||.||:..|.|..||.||.:|||.|:||||:.|.|.||.:
Human   291 STRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEE 355

  Fly   346 LFEAETNEAARLAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLMSTESLSPGALMAFLVASQG 410
            .:.||.......|::||.|||:||||:|...|.:||.|||:||.|::.:.|:.|.||:||||||.
Human   356 RYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQT 420

  Fly   411 VQRSLAQGSILLGTMIRGMSAGSRVFEFLSLQPQVELLRGYIIPQERLHGEIRFENVSFAYPMQP 475
            ||||:|..|:|.|.::||:|||:||||:::|.|.:.|..|..:|:|:|.|.:.|:||.|:||.:|
Human   421 VQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRP 485

  Fly   476 DHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVERFYEPSAGNIKLDGYKLSDISPYWLRSNV 540
            ...|||||:|||.||:.|||||.||.||:|:|||:||||:|:||.:.|||..|..:.|.|||..|
Human   486 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQV 550

  Fly   541 LGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDGYATHVGERGTQLSGG 605
            :|||.|:||||||:|:||||:||.:|.:|:||.|||.:.:|:|:|:.|:||.|.||||||.||||
Human   551 VGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVGERGTTLSGG 615

  Fly   606 QRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQNRTTLVIAHRLSTIRNADLIV 670
            |:||:||||||:|.|.:||||||||||||.||..||:|||.....||.|||||||||:|.|..||
Human   616 QKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHCIV 680

  Fly   671 VLDQGRVVETGKHDELMGKRGLYFELVRQQ 700
            |:..|||.|.|.|:||:.|.|||.||:|:|
Human   681 VMADGRVWEAGTHEELLKKGGLYAELIRRQ 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	311/582 (53%)
ABCB8	NP_001269220.1	MdlB	134..714	CDD:440747	311/582 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	712..735