DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT1G61590

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_176353.1	Gene:	AT1G61590 / 842455	AraportID:	AT1G61590	Length:	424	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	103/451 - (22%)
Similarity:	177/451 - (39%)	Gaps:	110/451 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 ATNASTTIPP--AAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHP-------QLYDLSRTQS 385
            :|.|||...|  ...|:....:.::....:||:....:.:..::...|       ...||||:.|
plant     5 STTASTKSSPLWKPFASNCCSVDDQTVFGNLSRCRPSRSEFSKNHLGPLPSFRRLSFADLSRSSS 69

  Fly   386 CRVVQKPQRIFRATDLVIGEK---------------LGEGFFGKVFK------VTHRQSGEVMVL 429
            .|:.:...:...| |||..:.               ||||.||||:|      :......:.:.:
plant    70 ARINEDLAQTLGA-DLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYVDDYLRQSLKAQPVAV 133

  Fly   430 KELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLK-ELIHDPAQV 493
            |.|.....:..|.::.||..|..|.|.:::|.||...::::..::.|::..|.|: .|....:..
plant   134 KLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIYEFMPRGSLENHLFRRISLS 198

  Fly   494 LPWPQRVRLARDIACGMSYLHSMN--IIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGN 556
            |||..|:::|...|.|:::||.:.  ||:||..:.|.|:..|.:..::|||||:
plant   199 LPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILLDSDFTAKLSDFGLAK----------- 252

  Fly   557 MTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIM 621
                           |.|.|:.....:|       |:|...:.|||.:.......|.||:|:|::
plant   253 ---------------MGPEGSKSHVTTR-------VMGTYGYAAPEYVSTGHLTTKSDVYSYGVV 295

  Fly   622 LCEIIGRVEADPDFMPRNS----DFS------------LNQQEFREKFCAQCPEPFVKVAFVCCD 670
            |.|::....|.....|:|.    |:|            :.......::..:..:....:|..|..
plant   296 LLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKAAKDTALLALQCVS 360

  Fly   671 LNPDMRP----CFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSED-ALSPTSQ 726
            .||..||    ..|.|                  |.|:|    :::...||.. .|||.||
plant   361 PNPKDRPKMLAVVEAL------------------ESLIH----YKDMAVSSGHWPLSPKSQ 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	74/314 (24%)
AT1G61590	NP_176353.1	STKc_IRAK	105..379	CDD:270968	75/324 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000