DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT1G60630

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_176262.2	Gene:	AT1G60630 / 842357	AraportID:	AT1G60630	Length:	652	Species:	Arabidopsis thaliana

Alignment Length:	379	Identity:	83/379 - (21%)
Similarity:	135/379 - (35%)	Gaps:	108/379 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 KEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQKPQR---------------IFRAT 399
            |.:||   .||.:.|..:|:          .:.|:.....||.:|               :|...
plant   285 KREER---RSKRVAESKEAK----------TAETEEGTSDQKNKRFSWEKESEEGSVGTLVFLGR 336

  Fly   400 DLVI------------GEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRL 452
            |:.:            .|.||.|..|..:|.. .:||.::.:|.|..|.......|.:.:.:|..
plant   337 DITVVRYTMDDLLKASAETLGRGTLGSTYKAV-MESGFIITVKRLKDAGFPRMDEFKRHIEILGR 400

  Fly   453 LDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIH-----DPAQVLPWPQRVRLARDIACGMSY 512
            |.|.:::.........::..:|.:|...|.|..|||     ...:.|.|...:::|.|:|.|:.|
plant   401 LKHPNLVPLRAYFQAKEECLLVYDYFPNGSLFSLIHGSKVSGSGKPLHWTSCLKIAEDLAMGLVY 465

  Fly   513 LH-SMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSG 576
            :| :..:.|.:|.|.|.|:..|....:.|:||:...|                      |.|...
plant   466 IHQNPGLTHGNLKSSNVLLGPDFESCLTDYGLSDLHD----------------------PYSIED 508

  Fly   577 TLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYD-EKVDVFSFGIMLCEII-GRVEADPDFMPRN 639
            |...|.              ::.|||.....|.. :..||:|||::|.|:: ||...........
plant   509 TSAASL--------------FYKAPECRDLRKASTQPADVYSFGVLLLELLTGRTSFKDLVHKYG 559

  Fly   640 SDFS----------------LNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRP 677
            ||.|                ||..|  ||.     :..:.:|..|..:.|:.||
plant   560 SDISTWVRAVREEETEVSEELNASE--EKL-----QALLTIATACVAVKPENRP 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	69/295 (23%)
AT1G60630	NP_176262.2	LRRNT_2	23..55	CDD:285463
		LRR_4	87..122	CDD:289563
		leucine-rich repeat	88..110	CDD:275380
		LRR_8	110..169	CDD:290566
		leucine-rich repeat	111..134	CDD:275380
		leucine-rich repeat	135..158	CDD:275380
		leucine-rich repeat	159..180	CDD:275380
		S_TKc	354..614	CDD:214567	70/297 (24%)
		PKc_like	356..616	CDD:304357	69/295 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000