DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT5G61560

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_001330716.1	Gene:	AT5G61560 / 836277	AraportID:	AT5G61560	Length:	815	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	115/533 - (21%)
Similarity:	199/533 - (37%)	Gaps:	131/533 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 WLTSMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPV 275
            |.:|..|:...:....|                  |.|.||  ||.|    :.::.:|.:|...:
plant   288 WRSSQMEEASSSSTYSD------------------PTSSSS--QIHK----DFELEKLKIELRHI 328

  Fly   276 QVCRSCSQADI-----------QRAMSASTLILPLSTSASS----VEVGRERLYKTPGEQGTKAR 325
            :...:.:|:::           ||....:|.:..|:.....    ||:.|||......|    |.
plant   329 KGMYAVAQSEVIDASKKMQDLNQRRSEEATRLKNLTIREEEADEVVEMERERQEDAENE----AE 389

  Fly   326 KLRQATNASTTIPPAAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQ 390
            .:|:.....|.....|.|.|....|||:|   |...|:         ..|    |.|.|..:.
plant   390 LVRECIERETEERLEAEARAEEVRKEKQR---LEDALE---------GGP----LQRQQYMKF-- 436

  Fly   391 KPQRIFRATDLVIGE-KLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLD 454
            :.:.|..||.....| |:|.|.:|.|::.....:  .:.:|.||.......:.|.:|:.:|..:.
plant   437 EWEEIVEATSSFSDELKIGVGGYGSVYRCNLHHT--TVAVKVLHSDKSSLTKQFHQELEILSKIR 499

  Fly   455 HRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIH------DPAQVLP--WPQRVRLARDIACGMS 511
            |.|:|..:|..  .::..:|.||:..|.|:|.:.      |..|..|  |.:|.|:|.:||..:.
plant   500 HPHLLLLLGAC--PERGSLVYEYMHNGSLEERLMKRRPNVDTPQPPPLRWFERFRIAWEIASALY 562

  Fly   512 YLHSMN---IIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMS 573
            :||:..   |:||||...|.|:..:....:.|.||::.|        |:.|....:..|...|
plant   563 FLHTNEPRPIVHRDLKPANILLDRNNVSKIGDVGLSKMV--------NLDPSHASTVFNETGP-- 617

  Fly   574 PSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPR 638
                               ||..:::.||..:......:.|:::|||:|.:::....|..  :..
plant   618 -------------------VGTFFYIDPEYQRTGVVTPESDIYAFGIILLQLVTARSAMG--LAH 661

  Fly   639 NSDFSLNQQ-----EFREKFCAQCP----EPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLA 694
            :.:.:|..|     |..:|.....|    :..|.:...|.::....||              ||.
plant   662 SIEKALRDQTGKFTEILDKTAGDWPVKEAKEMVMIGLRCAEMRKRDRP--------------DLG 712

  Fly   695 ADRVPPERLLHEI 707
            .:.:|....|.|:
plant   713 KEILPVLERLKEV 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492	12/59 (20%)
		STKc_LIMK	407..693	CDD:271056	65/305 (21%)
AT5G61560	NP_001330716.1	STK_N	26..173	CDD:238947
		Smc	<317..>424	CDD:224117	24/113 (21%)
		PKc_like	454..722	CDD:419665	68/316 (22%)
		Ubox	747..809	CDD:128780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000