DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT5G47070

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_199518.1	Gene:	AT5G47070 / 834753	AraportID:	AT5G47070	Length:	410	Species:	Arabidopsis thaliana

Alignment Length:	383	Identity:	101/383 - (26%)
Similarity:	169/383 - (44%)	Gaps:	88/383 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 QHSAHPQLYDLSRT-----QSCRVVQKPQ-------------RIFRATDL-----VIGEKL--GE 409
            |:|| |:|.:.|.|     |:.|.:..|:             |:|...:|     |...||  ||
plant    31 QNSA-PELTNRSETSSFNLQTPRSLPSPRSIKDLYTEREQNLRVFSYEELSKATYVFSRKLVIGE 94

  Fly   410 GFFGKVFKVTHRQSGE------VMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKD 468
            |.||.|:|.....:|:      |:.:|:|:|...:..:.::.||..|.:::|.:|:|.||...:|
plant    95 GGFGIVYKGKILSNGDSSDPPLVVAIKKLNRQGLQGHKQWLAEVQFLGVVNHPNVVKLIGYCSED 159

  Fly   469 -----KKLHMVTEYVAGGCLKE-LIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMN 527
                 ::| :|.||::...|:: |....:..|||.:|:.:....|.|::|||.:.:|:||..|.|
plant   160 GETGIERL-LVYEYMSNRSLEDHLFPRRSHTLPWKKRLEIMLGAAEGLTYLHDLKVIYRDFKSSN 223

  Fly   528 CLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTV 592
            .|:.:.....::||||||..     |.|:.|                ..|..|
plant   224 VLLDDQFCPKLSDFGLAREG-----PDGDNT----------------HVTTAR------------ 255

  Fly   593 VGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEII-GR--VEADPDFMPRN-----SDFSLNQQEF 649
            ||...:.|||.::......|.||:|||::|.||| ||  :|.:.....|.     .::..:.|.|
plant   256 VGTHGYAAPEYVQTGHLRLKSDVYSFGVVLYEIITGRRTIERNKPVAERRLLDWVKEYPADSQRF 320

  Fly   650 --------REKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVP 699
                    |..:.|.......|:|.:|...|...||..|.:...|:::.::..::..|
plant   321 SMIVDPRLRNNYPAAGARSLAKLADLCLKKNDKERPTMEIVVERLKKIIEESDSEDYP 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	85/315 (27%)
AT5G47070	NP_199518.1	STYKc	91..365	CDD:214568	83/307 (27%)
AT5G47070	NP_199518.1	STKc_IRAK	92..368	CDD:270968	84/309 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000