DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and CRK10

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_567679.2	Gene:	CRK10 / 828417	AraportID:	AT4G23180	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	333	Identity:	86/333 - (25%)
Similarity:	139/333 - (41%)	Gaps:	80/333 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 DLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGV 464
            |.|...|:|:|.||:|:|.|.....||.| |.|.::..:.:..|..||.::..|.||::::.:|.
plant   347 DFVESNKIGQGGFGEVYKGTLSDGTEVAV-KRLSKSSGQGEVEFKNEVVLVAKLQHRNLVRLLGF 410

  Fly   465 LYKDKKLHMVTEYVAGGCLKELIHDPAQ--VLPWPQRVRLARDIACGMSYLHS---MNIIHRDLN 524
            ....::..:|.|||....|...:.|||:  .|.|.:|.::...:|.|:.|||.   :.||||||.
plant   411 CLDGEERVLVYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVARGILYLHQDSRLTIIHRDLK 475

  Fly   525 SMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQR 589
            :.|.|:..|.:..:||||:||.               :|              |.:::....|
plant   476 ASNILLDADMNPKIADFGMARI---------------FG--------------LDQTEENTSR-- 509

  Fly   590 YTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEII-GRVEADPDFMPRNSDFSLNQ------- 646
              :||...:|:||.....:|..|.||:|||:::.||| |:         :||.|....
plant   510 --IVGTYGYMSPEYAMHGQYSMKSDVYSFGVLVLEIISGK---------KNSSFYQTDGAHDLVS 563

  Fly   647 --------------------QEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLAD 691
                                :..:.....:|    |.:..:|...:|..||...|:.:.|.....
plant   564 YAWGLWSNGRPLELVDPAIVENCQRNEVVRC----VHIGLLCVQEDPAERPTLSTIVLMLTSNTV 624

  Fly   692 DLAADRVP 699
            .|...|.|
plant   625 TLPVPRQP 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	80/318 (25%)
CRK10	NP_567679.2	Stress-antifung	43..138	CDD:279926
		TyrKc	353..619	CDD:197581	80/312 (26%)
		STKc_IRAK	354..620	CDD:270968	79/312 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000