DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT3G50730

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_190642.2	Gene:	AT3G50730 / 824237	AraportID:	AT3G50730	Length:	371	Species:	Arabidopsis thaliana

Alignment Length:	433	Identity:	115/433 - (26%)
Similarity:	182/433 - (42%)	Gaps:	102/433 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 LSKLLDEQHQAQQHS-AHPQLYDLSRTQSCRVVQKPQRIFRATDLVIGEKLGEGFFGKVFKVTHR 421
            :|:::...:.:...| ..|..:.:||          :.:....|:|:||.:|||.:..|:|...|
plant     2 ISRMIFRNYPSHNESDDEPFHFSISR----------ELLLDRNDVVVGEMIGEGAYSIVYKGLLR 56

  Fly   422 QSGEVMVLKELHRADEEA-----QRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGG 481
            ....|.| |.:..:...|     ::.|.|||.:|..:.|.:::||:|... :.:|.:|||.|.||
plant    57 NQFPVAV-KIMDPSTTSAVTKAHKKTFQKEVLLLSKMKHDNIVKFVGACI-EPQLIIVTELVEGG 119

  Fly   482 CLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVRED-RSVIVADFGLAR 545
            .|:..:|.....|.....:..|.||:..|.::||..|||||||..|.||..| :.|.:||||:||
plant   120 TLQRFMHSRPGPLDLKMSLSFALDISRAMEFVHSNGIIHRDLNPRNLLVTGDLKHVKLADFGIAR 184

  Fly   546 SVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMM------ 604
                      ..|.||....|                           |...|||||::
plant   185 ----------EETRGGMTCEA---------------------------GTSKWMAPEVVYSPEPL 212

  Fly   605 ---KGLKYDEKVDVFSFGIMLCEIIGRVEADPD-----FMPRNSDFSLNQQEFREKFCAQCPEPF 661
               :..:||.|.|::||.|:|.:::...|..||     |:|    :.::|.  |.....:.|:.|
plant   213 RVGEKKEYDHKADIYSFAIVLWQLVTNEEPFPDVPNSLFVP----YLVSQG--RRPILTKTPDVF 271

  Fly   662 VKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQ 726
            |.:...|...:||.||.|:.:.|.|..|...:::|                   ||.....|..:
plant   272 VPIVESCWAQDPDARPEFKEISVMLTNLLRRMSSD-------------------SSIGTTLPDGE 317

  Fly   727 RSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGK 769
            .....::|       ||.||:.:|....|.||::..|...|.|
plant   318 AYEGEMEE-------SENSPLLQEHFCKVKKPKEKKKKKKLVK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	90/305 (30%)
AT3G50730	NP_190642.2	TyrKc	36..292	CDD:197581	90/300 (30%)
AT3G50730	NP_190642.2	STKc_MAP3K-like	42..296	CDD:270901	88/298 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910