DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT2G45910

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_001324111.1	Gene:	AT2G45910 / 819199	AraportID:	AT2G45910	Length:	834	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	116/524 - (22%)
Similarity:	193/524 - (36%)	Gaps:	129/524 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 STSASSVEVGR------------ERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKEK 352
            |.||.|.|:.|            ||......||.....:|:.|......:......:..|..|..
plant   353 SESAYSEELKRRKDTEIAVAKEKERFITIKNEQEVIMEELQSAMAQKAMLESQIAKSDGTMEKLN 417

  Fly   353 ERCSSLSKLLD------EQHQAQQHSAHPQLYDLSRTQSCRVVQKPQRIFRATDLVIGE------ 405
            ::.....|||.      |:.|.::..|..:..:|........:|.||..   ||....|
plant   418 QKLDIAVKLLQKLRDEREELQTERDRALREAEELRSHAETSTLQLPQYF---TDFSFSEIEEATN 479

  Fly   406 ------KLGEGFFGKVF--KVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFI 462
                  |:|||.:|.::  .:.|.|    :.:|.|:....:....:.:||.||..:.|.:::..|
plant   480 HFDSTLKIGEGGYGSIYVGLLRHTQ----VAIKMLNPNSSQGPVEYQQEVDVLSKMRHPNIITLI 540

  Fly   463 GVLYKDKKLHMVTEYVAGGCLKELI--HDPAQVLPWPQRVRLARDIACGMSYLHS---MNIIHRD 522
            |...:...|  |.||:.||.|::.:  .|.:..|.|..|||:|.:|...:.:|||   .:::|.|
plant   541 GACPEGWSL--VYEYLPGGSLEDRLTCKDNSPPLSWQNRVRIATEICAALVFLHSNKAHSLVHGD 603

  Fly   523 LNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRR 587
            |...|.|:..:....::|||..                         :.:.|:|    |||
plant   604 LKPANILLDSNLVSKLSDFGTC-------------------------SLLHPNG----SKS---- 635

  Fly   588 QRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIG-----RVEADPDFMPRNSDFSLNQQ 647
            .|..|.|...::.||.....:...|.||:||||:|..::.     |:..:..:...|.  :||
plant   636 VRTDVTGTVAYLDPEASSSGELTPKSDVYSFGIILLRLLTGRPALRISNEVKYALDNG--TLN-- 696

  Fly   648 EFREKFCAQCP----EPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAAD------------ 696
            :..:......|    |...::|..||:...:.||...| .||  |:.:.:.|.
plant   697 DLLDPLAGDWPFVQAEQLARLALRCCETVSENRPDLGT-EVW--RVLEPMRASSGGSSSFHLGRN 758

  Fly   697 --RVPP-------------------ERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAV 740
              |:.|                   :...:|.|..:.|..|..|. ||.:...|::...:...|:
plant   759 EHRIAPPYFICPIFQEVMQDPHVAADGFTYEAEAIRAWLDSEHDT-SPMTNVKLSHTSLIANHAL 822

  Fly   741 DSEI 744
            .|.|
plant   823 RSAI 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	74/301 (25%)
AT2G45910	NP_001324111.1	STK_N	46..199	CDD:238947
		Smc	<313..>519	CDD:224117	36/172 (21%)
		STKc_IRAK	487..743	CDD:270968	74/301 (25%)
		Ubox	766..829	CDD:128780	11/62 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000