DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIMK1 and AT2G07180

DIOPT Version :9

Sequence 1:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster
Sequence 2:	NP_001189514.1	Gene:	AT2G07180 / 815287	AraportID:	AT2G07180	Length:	442	Species:	Arabidopsis thaliana

Alignment Length:	405	Identity:	104/405 - (25%)
Similarity:	161/405 - (39%)	Gaps:	109/405 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 IFRATDLVIGEK-------LGEGFFGKVFKVTHRQSGEV------MVLKELHRADEEAQRNFIKE 446
            ||...::.|..|       ||||.||.|:|....:|..|      :.:|||:....:..|.::.|
plant    77 IFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVGFKSTKVAIKELNPEGFQGDREWLAE 141

  Fly   447 VAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCL-KELIHDPAQVLPWPQRVRLARDIACGM 510
            |..|..|.|.:::|.||...:|....:|.||:|.|.| |.|.......|.|.:|:::|.|.|.|:
plant   142 VNYLGQLSHPNLVKLIGYCCEDDHRLLVYEYMAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGL 206

  Fly   511 SYLH--SMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMS 573
            ::||  ..:||:|||.:.|.|:.|..:..::|||||:  |.||   |:.|
plant   207 AFLHGAERSIIYRDLKTANILLDEGYNAKLSDFGLAK--DGPR---GDQT--------------- 251

  Fly   574 PSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCE-IIGRVEADPDFMP 637
                  ...:|       |:|...:.|||.:.......:.||:.||::|.| ::|:...|
plant   252 ------HVSTR-------VMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEMLLGKRAMD----- 298

  Fly   638 RNSDFSLNQQEFREKFCAQCPEPFVK---------------------------VAFVCCDLNPDM 675
                   ..:..||....:...|.:.                           :|:.|...||..
plant   299 -------KSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLAYQCLSQNPKG 356

  Fly   676 RPCFETLHVWLQRLADD-LAADRVPPERLLHEIETFQEWYASSEDALS-----------PTSQRS 728
            ||....:...|:.|.|| .|.:.|...  ||........|.:|.|:..           |.|.||
plant   357 RPLMNHVVEVLETLKDDGDAQEEVMTN--LHSRGKSVTLYEASSDSQGTRDGNGQRRRRPESGRS 419

  Fly   729 LNNLDELVKSAVDSE 743
            .:      ::|||:|
plant   420 KS------EAAVDTE 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	85/323 (26%)
AT2G07180	NP_001189514.1	STKc_IRAK	96..370	CDD:270968	82/318 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000