Protein Alignment LIMK1 and si:ch211-45c16.2

DIOPT Version :9

• Sequence 1: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Sequence 2: XP_017213349.1
• Gene: si:ch211-45c16.2 / 568412
• ZFINID: ZDB-GENE-081105-15
• Length: 982
• Species: Danio rerio
• Alignment Length: 838
• Identity: 186/838 - (22%)
• Similarity: 293/838 - (34%)
• Gaps: 271/838 - (32%)

  Fly   407 LGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKL 471
            ||.|..|.||....|  .|.:.:|::....|       .::..||.|.|.:::.|.||..:....
Zfish   226 LGSGAQGAVFLGKFR--SEEVAIKKVREQKE-------TDIKHLRKLKHPNIISFKGVCTQAPCY 281

  Fly   472 HMVTEYVAGGCLKELIH-----DPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVR 531
            .::.||.|.|.|.|::.     .|..::.|      |..||.||:|||...||||||.|.|.||.
Zfish   282 CIIMEYCAQGQLYEVLRAGRKITPCLLVDW------ASGIASGMNYLHLHKIIHRDLKSPNVLVT 340

  Fly   532 EDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNP 596
            ::.||.::|||.::.:                  ::....||.:||:.
Zfish   341 QNDSVKISDFGTSKEL------------------SDKSTKMSFAGTVA----------------- 370

  Fly   597 YWMAPEMMKGLKYDEKVDVFSFGIMLCEII-GRV---EADPDFMPRNSDFSLNQQEFREKFCAQC 657
             |||||:::.....||||::|||::|.|:: |.:   :.|...:    .:.:..........:.|
Zfish   371 -WMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAI----IWGVGSNSLHLPVPSTC 430

  Fly   658 PEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRV--PPERLLHEIETFQEWYASSEDA 720
            |:.|..:........|..||.|..:.:.|     |:|:..|  .|:....:.:|  ||
Zfish   431 PDGFKILMKQTWQGKPRNRPSFRQILLHL-----DIASADVLGTPQETYFKCQT--EW------- 481

  Fly   721 LSPTSQRSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRAR 785
                 :..:....|.:||             |...|                   .||.:.:..|
Zfish   482 -----REEVKKHFEKIKS-------------EGTCI-------------------HRLDEELIRR 509

  Fly   786 RRQRFLGAQEERRNLTPDTESKERALKKALKKCRPFGERGYLVDLRAGAELQLEDVRD---LNTY 847
            ||       :|.|:.....|..||.|::|         ....::|.| ..|||| ||:   |...
Zfish   510 RR-------DELRHALDIREHYERKLERA---------NNLYMELSA-IMLQLE-VREKELLKRE 556

  Fly   848 SDVDSSCDTSLNYHDVNNLPAAQEDENTVKPGK-EELLEEST---NKPSNQESQHHRLAIDD--- 905
            ..|:.....:...|.|..:         |:|.. |:|:::.:   :||..|:.:...|...|
Zfish   557 QAVEKKYPGTYKRHLVRPI---------VRPNAVEKLIKKKSSMNHKPGTQQPKRPDLLRSDGIP 612

  Fly   906 ---------------------MRTRLNQCRSKFEHLEEASRRNFNQSQHSMKNFFKTPPVALKMF 949
                                 .:||.   |||..|     ||..::..|   |.|   |..||..
Zfish   613 SVEPLPAPSPLSGSPKVSTPPGKTRY---RSKPRH-----RRANSKGSH---NEF---PGVLKPN 663

  Fly   950 QRLEHEAAALNGGN---NCPPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAK 1011
            .....|...|...|   |.|.|||      :.|:...:...||.....|::         .|.|.
Zfish   664 SGPPEEQQPLQEQNYLQNHPLPPP------EPPLAKTRENAVATCANNLRY---------FGPAA 713

  Fly  1012 QLATPAPKRSKATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKK 1076
            .|.:|.....:...:     .|:|.|       ||.|::::..:     ..||.||..:
Zfish   714 ALRSPQTDHLQRRLS-----GSSPDL-------ISTAVDADSRL-----RRSSIPPGPA------ 755

  Fly  1077 HKLTLPL-PSAQQQRTSSNHRLPMCNNKGKTLKPLPSRTGSQGIPASNCVSPTRSSRPGSPTKHL 1140
                 || |..|.      |..|.|.:..:|    |:......:|..:.:|....:.|.|
Zfish   756 -----PLCPCCQA------HPFPGCKHCQQT----PAAPSHPQLPHYSLLSTNDGTPPAS----- 800

  Fly  1141 AQRHTAATAQRLTNAAATHQQQHQQQSSKTTRLNILSPEKVHRLGARLTDQKQKMREE 1198
             :|:...||            :.|.:..|...|:.|.|       .|.|..:....||
Zfish   801 -KRNLEPTA------------EGQDKEEKPALLHTLRP-------LRKTGDESSEEEE 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	76/294 (26%)
si:ch211-45c16.2	XP_017213349.1	STKc_MAP3K12_13	226..462	CDD:270961	77/295 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910