Protein Alignment LIMK1 and tesk1a

DIOPT Version :10

• Sequence 1: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Sequence 2: XP_021332499.1
• Gene: tesk1a / 556048
• ZFINID: ZDB-GENE-090312-74
• Length: 657
• Species: Danio rerio
• Alignment Length: 780
• Identity: 216/780 - (27%)
• Similarity: 310/780 - (39%)
• Gaps: 192/780 - (24%)

  Fly   370 QHSAHPQLYDL-----SRTQSCRVVQKPQRIFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVL 429
            |....|.|:.|     .|..|.|.::.........|....||:|.|||.:||||.||.:|:||.|
Zfish     7 QEPCEPPLHALYGPNRIRPSSYRALRSAVSSLARIDDFFCEKIGSGFFSEVFKVQHRITGQVMAL 71

  Fly   430 KELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVL 494
            |....|..:|  |.::||.::..|.|.::|:|:||...:.:||.:|||:.||.|::|: |....|
Zfish    72 KMNTLASNKA--NMLREVQLMNRLCHPNILRFLGVCVHEGQLHALTEYINGGNLEQLL-DSDIYL 133

  Fly   495 PWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDR---SVIVADFGLARSVDAPRLPSGN 556
            .|..|:.|:.|||.|:.||||..|.||||.|.|||||.:.   :.:|.|||||.     ::|.
Zfish   134 SWTVRIGLSLDIARGLQYLHSKGIFHRDLTSKNCLVRCENGAFTAVVGDFGLAE-----KIPD-- 191

  Fly   557 MTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIM 621
                 |..|.                   .:|...|||:||||||||::|..|:||||||::||:
Zfish   192 -----YSDGV-------------------EKQPLAVVGSPYWMAPEMLRGELYNEKVDVFAYGII 232

  Fly   622 LCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWL 686
            |||||.|:|||||.:||..||.|:...| |.....||..|:::|..||::|.|.||.|..:.|.|
Zfish   233 LCEIIARIEADPDILPRTEDFGLDVDTF-EHMVGDCPPSFLQMAVDCCNMNADSRPAFSEIVVML 296

  Fly   687 QRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAVDSEISPVEKEK 751
            :|:..:.....:|.  :|..|......|........|..||...:..:::..|.
Zfish   297 ERIERERVKSEIPV--ILEPIAIDVSPYRRRSSPCHPCDQRLSRSQSDMLPPAT----------- 348

  Fly   752 ENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRARRRQRFLGAQEERRNLT------PDTE----- 805
                        ||.||.....:...||..:...|.:.|....:...:||      ||..
Zfish   349 ------------SPCLGTPARVNPFSLRQDLNGGRIKLFDTPSKSVISLTFTLPPPPDPSASPPL 401

  Fly   806 SKERALKKALKKCR------------PFGERGYLVDLRAGAELQLEDVRDLNTYSDV--DSSCDT 856
            |....|:...::||            ||.::....|.......:.:| ::|....|.  ||....
Zfish   402 SGSPGLRGPPRRCRSLPCTPELGRQLPFRDQEVEEDRSEELGQETKD-KELEGQQDAVEDSGLVL 465

  Fly   857 SLNYHDVNNLPAAQEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRLNQCRSKFEHLE 921
            .|:...:..:...:|||...|.|      :|..:|.:                   |.|..:..|
Zfish   466 DLDMVSLERVEEEEEDEEVEKEG------QSLTEPMD-------------------CSSSPDTTE 505

  Fly   922 --EASRRNFNQSQHS---MKNFFKTP----PVALKMFQRLEHEAAALNGG------------NNC 965
              .:.:|..:.|.:|   ..|.:.||    |..|....||::....|..|            ...
Zfish   506 GNVSGKRLISGSSYSSSLQSNGWATPISNGPPLLPPLPRLDNNNGVLRPGRPFAWVRLNGYRGPA 570

  Fly   966 PPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAKQLATPAPKR--------SK 1022
            |.|.|.|::.:....     |...:.|      .|...|...|.......| |:|        ..
Zfish   571 PEPLPPTEQDDVISC-----PACCLAG------FSFPSLCLRGAPPSRRGP-PRRPYRTFNGGDA 623

  Fly  1023 ATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKKHKLTLPLPSAQ 1087
            :|||.||                   |...| .|....:.:||.|.            ||||.||
Zfish   624 STATAKG-------------------LLCRG-ATGLAPSTASCEPG------------LPLPEAQ 656

  Fly  1088  1087
            Zfish   657  656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_LIMK-like	169..274	CDD:467236
		STKc_LIMK	407..693	CDD:271056	122/288 (42%)
tesk1a	XP_021332499.1	PKc_TESK	49..303	CDD:271057	122/288 (42%)