Protein Alignment LIMK1 and raf1

DIOPT Version :9

• Sequence 1: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Sequence 2: XP_031755972.1
• Gene: raf1 / 549871
• XenbaseID: XB-GENE-6053330
• Length: 658
• Species: Xenopus tropicalis
• Alignment Length: 634
• Identity: 157/634 - (24%)
• Similarity: 237/634 - (37%)
• Gaps: 166/634 - (26%)

  Fly   173 RLVEIPKDATPGLRVD---------GVALD----DGCPT-----VRITDL---FCNF---FLWLT 213
            ||::.||..   ||:|         |..|.    |..|.     ||.|.|   ||:.   || |.
 Frog   100 RLIQDPKGK---LRLDWNTDAMSLVGAELQVDFLDHVPLTTHNFVRKTFLKLAFCDICQKFL-LN 160

  Fly   214 SMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQ--------LTV 270
            ....|.||  |:...:.:.        :|....|..|::.|:  |:..|...::        |||
 Frog   161 GFRCQTCG--YKFHEHCST--------KVPTMCVDWSNIRQL--LLFPNPNNMEGGSHTLPSLTV 213

  Fly   271 E--HDPVQVCRSCSQA-DIQRAMSASTLILPLSTSASSVEVGRERLYKTPG---EQGTKARKLRQ 329
            .  .:.|::..|..|. ......|.||...|...|.|.    |:|...||.   ...|.|...|.
 Frog   214 RRMRESVRIPISSQQRYSTPHPFSFSTPSAPSECSLSQ----RQRSTSTPNVHMVSTTMAVDSRL 274

  Fly   330 ATNASTTIPPAA--------GATAMTQLKEKERCSSLS-------KLLDEQHQAQQHSAHPQLYD 379
            ..|....:.|::        |..|:....:....::||       |.....|:.:..|:..|
 Frog   275 IENNWLNVSPSSWGRQLCMRGRDAVRSHSDSGSPNNLSPTGWSNTKTPAPTHREKAASSSGQ--- 336

  Fly   380 LSRTQSCRVVQKPQR------IFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEE 438
                :..::..:.||      ...|:::::..::|.|.||.|:|........|.:||..:...|:
 Frog   337 ----EKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVTNPTPEQ 397

  Fly   439 AQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLA 503
            .|. |..||||||...|.::|.|:|.:.|: .|.:||::..|..|.:.:|.........|.:.:|
 Frog   398 LQA-FRNEVAVLRKTRHVNILLFMGYMTKE-NLAIVTQWCEGSSLYKHLHVLETKFQMFQLIDIA 460

  Fly   504 RDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANS 568
            |..|.||.|||:.||||||:.|.|..:.|..:|.:.||||| :|.:
 Frog   461 RQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA-TVKS------------------- 505

  Fly   569 DAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPE---MMKGLKYDEKVDVFSFGIMLCE------ 624
                      |.|.|:|..|   ..|:..|||||   |.....:..:.||:|:||:|.|
 Frog   506 ----------RWSGSQQVEQ---PTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLFELMTGEL 557

  Fly   625 -------------IIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMR 676
                         ::||....||.               .|....||:...::...|.....:.|
 Frog   558 PYSHIRDRDQIIFLVGRGGTVPDL---------------SKLYKNCPKAMKRLVADCIKKMREER 607

  Fly   677 PCFETLHVWLQRLADDL-AADRVPPERLLHEIETFQEWYASSEDALSPT 724
            |.|..:...::.|...| ..:|...|..||..       |.:||..|.|
 Frog   608 PLFPQILSSIELLQHSLPKINRSASEPSLHRA-------AHTEDINSCT 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492	32/129 (25%)
		STKc_LIMK	407..693	CDD:271056	85/307 (28%)
raf1	XP_031755972.1	RBD_CRAF	56..130	CDD:340655	9/32 (28%)
		C1_A_C-Raf	135..186	CDD:410420	15/61 (25%)
		STKc_C-Raf	347..629	CDD:271051	88/331 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000