Protein Alignment LIMK1 and Ilk

DIOPT Version :9

• Sequence 1: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Sequence 2: NP_525001.2
• Gene: Ilk / 53573
• FlyBaseID: FBgn0028427
• Length: 448
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 93/452 - (20%)
• Similarity: 163/452 - (36%)
• Gaps: 121/452 - (26%)

  Fly   309 GRERLYKTPGEQGTKARKLRQATNASTTIP----PAAGATAMTQLKEKER--------------- 354
            |..:|.:|..::|::.    .|||....||    .|.|...:.|:..|||
  Fly    45 GHAKLVETLLQRGSRV----NATNMGDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLH 105

  Fly   355 ----------CSSLSK------LLDEQHQAQQHSAHPQLYDLSRTQSCRVVQKPQRIFR------ 397
                      |..|..      :.::........|.|.|  ..|.|.  :|:|..|..:
  Fly   106 YACFWGYDMICEDLLNAGAQVGIANKDGHTPLEKAKPSL--AKRLQD--LVEKSGREVKVISFKE 166

  Fly   398 ------------AT----------DLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQ 440
                        ||          ||.:..||.....|:.::...:::..|..:..:.:......
  Fly   167 QSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRIS 231

  Fly   441 RNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHD-PAQVLPWPQRVRLAR 504
            |:|.:|...||:..|.::|..||.......|..:::::....|..|:|. ...|:...|.|..|.
  Fly   232 RDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFAL 296

  Fly   505 DIACGMSYLHSMNII----HRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSG 565
            |:|.||::|||:..|    |  |||.:.::.:|.:..:                 ||
  Fly   297 DVARGMAFLHSLERIIPTYH--LNSHHVMIDDDLTARI-----------------NM-------- 334

  Fly   566 ANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYD---EKVDVFSFGIMLCEIIG 627
              .||..|     .:.|.|        :..|.||:||.::..:.|   |..|::||.|::.|:..
  Fly   335 --GDAKFS-----FQEKGR--------IYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTT 384

  Fly   628 RVEADPDFMPRNSDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRL 689
            |.....::.|......:..:..|.|..........|:..:|.:.:|..||.|:.:...|:::
  Fly   385 REVPFAEWSPMECGMKIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKFDMVVPILEKM 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	63/291 (22%)
Ilk	NP_525001.2	ANK	28..140	CDD:238125	17/98 (17%)
		ANK repeat	33..64	CDD:293786	5/22 (23%)
		Ank_2	38..130	CDD:289560	17/88 (19%)
		ANK repeat	66..97	CDD:293786	8/30 (27%)
		ANK repeat	99..130	CDD:293786	2/30 (7%)
		PK_ILK	196..446	CDD:270959	64/291 (22%)
		STYKc	204..443	CDD:214568	61/280 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930