Protein Alignment LIMK1 and Takl2

DIOPT Version :10

• Sequence 1: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Sequence 2: NP_651090.2
• Gene: Takl2 / 42692
• FlyBaseID: FBgn0039015
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 313
• Identity: 80/313 - (25%)
• Similarity: 128/313 - (40%)
• Gaps: 70/313 - (22%)

  Fly   405 EKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDK 469
            |.:|.||:|.|::...|  ...:.||.:....|:  :...:|:..|....|.::::..|....:.
  Fly    17 ELIGTGFYGSVYRAVWR--NREIALKRIREGCED--KKIEREIYQLTKASHVNIVELYGTSRHEG 77

  Fly   470 KLHMVTEYVAGGCLKELIH-------DPAQVLPWPQRVRLARDIACGMSYLHSMN---IIHRDLN 524
            ...::.|:|.||.|...:|       ..|....|      |..||.|::|||.|.   :||||:.
  Fly    78 CALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNW------AHQIAQGIAYLHGMQPKAVIHRDIK 136

  Fly   525 SMNCLVRE-DRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQ 588
            .:|.|:.| ...:.:.|||..  ||..:..|.|                  :||.|
  Fly   137 PLNTLLCEKGLKLKICDFGTV--VDLSQSISCN------------------AGTCR--------- 172

  Fly   589 RYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSL----NQQEF 649
                     :.|||:::|.|.|||.||:|:.|...||:.|.|   .|...|:.|.|    |:.|.
  Fly   173 ---------YKAPEVLQGNKPDEKCDVYSWAITFWEILSRKE---PFEQYNTLFELYMAINEGER 225

  Fly   650 REKFC--AQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPP 700
            .:..|  :.||...|.:.:...|.:...|...|.:...:.|:..:  |..:||
  Fly   226 PDLSCIMSGCPADIVALLYASWDPDISKRFSMELISQSMGRILSE--AGSIPP 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_LIMK-like	169..274	CDD:467236
		STKc_LIMK	407..693	CDD:271056	76/302 (25%)
Takl2	NP_651090.2	Protein Kinases, catalytic domain	19..268	CDD:473864	76/299 (25%)