DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pits and Myt1

DIOPT Version :9

Sequence 1:NP_001138192.1 Gene:Pits / 32205 FlyBaseID:FBgn0030400 Length:630 Species:Drosophila melanogaster
Sequence 2:XP_038961498.1 Gene:Myt1 / 362291 RGDID:1304899 Length:983 Species:Rattus norvegicus


Alignment Length:512 Identity:99/512 - (19%)
Similarity:151/512 - (29%) Gaps:181/512 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 AVCR-GCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHENGEVSAAAAAAVVLQQQQQLQVGPV 92
            |||. ||...|     :..|......|...|....::|..|.:.|..        ::::::. |.
  Rat   475 AVCESGCPPAE-----QGHLGPGEPGKMAKPLDVVRKSCYNKDPSRV--------EKREIKC-PT 525

  Fly    93 PG-QGPG------SHRGGGGGGP--PGAPP----------GSGGPGPSGAGSLSSLGNA------ 132
            || .|.|      .|.....|.|  ...||          ....||.:|.|.::|..|.      
  Rat   526 PGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSG 590

  Fly   133 --VAAAAAAAAVHHHHQMPYQMP------VPRIGPPLDYPVKLEDAPGGGVRP------------ 177
              :|||...|..|...|:....|      ..||..|:.:..:||..|.|..||            
  Rat   591 CPIAAAEKLAKSHEKQQLQTGDPPKNNSNSDRILRPMCFVKQLEVPPYGSYRPNVAPTTPRANLA 655

  Fly   178 -----------------------------VRISHMTPH--------------HLPPNATRGGGGA 199
                                         ::.|..:|.              |:...|       
  Rat   656 KELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSHDAEAAHMAATA------- 713

  Fly   200 PGGGVPTAGSGGGSLPPALSVNLKRPPSEDVDVDV---------------------SQQQQQSGH 243
                :....:....:|..||...:..||:.||::|                     |.....|..
  Rat   714 ----ILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSP 774

  Fly   244 GL-APDGSAGNSLSAGGGVSGGCPPGIKRSAMDD---------PSGVGGRPPLTRGESLPAAVSY 298
            |: :||.|...|.::....|...|...:.|..|:         ||.:....|   .||.|||.|:
  Rat   775 GVKSPDVSQRQSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEP---EESEPAAHSF 836

  Fly   299 VPERQLSGLRDKQQPVRAPSFDASTFKAANPIPN-----------------PIP---HHLHIAEH 343
            .     |...|.|: |...:|:...:.....:.|                 |.|   ...||..:
  Rat   837 A-----SSEADDQE-VSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGN 895

  Fly   344 MSPASRRNGSSPPSGPLPPRSV---HSPNSSGSSSGRRSSGSRHVSSTTVTSSEVGG 397
            .  ||.|:.|..|......|::   ||.:....:.|  ..||.|::....:...:.|
  Rat   896 Y--ASHRSLSGCPLADKSLRNLMAAHSADLKCPTPG--CDGSGHITGNYASHRSLSG 948

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PitsNP_001138192.1 IRF-2BP1_2 6..57 CDD:288155 8/28 (29%)
zf-C3HC4 548..593 CDD:278524
Myt1XP_038961498.1 zf-C2HC 111..138 CDD:396216
zf-C2HC 522..548 CDD:396216 7/26 (27%)
zf-C2HC 566..594 CDD:396216 6/27 (22%)
MYT1 641..872 CDD:400668 40/250 (16%)
zf-C2HC 880..908 CDD:396216 9/29 (31%)
zf-C2HC 924..952 CDD:396216 5/27 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166352352
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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