Protein Alignment Pits and ifbp-1

DIOPT Version :10

• Sequence 1: NP_001138192.1
• Gene: Pits / 32205
• FlyBaseID: FBgn0030400
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_506317.2
• Gene: ifbp-1 / 179817
• WormBaseID: WBGene00010867
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 146/632 - (23%)
• Similarity: 187/632 - (29%)
• Gaps: 335/632 - (53%)

  Fly     7 RQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHENGEV 71
            ||.||||||||.|||:|||:.|.||||||||||:||||.||:..||.|:|......  ..:|.:.
 Worm    76 RQQCYLCDLPRWPWAIINDYIEPVCRGCVNYEGSDRIELVLEETRQQKKLQGVGIS--DPQNAKT 138

  Fly    72 SAAAAAAVVLQQQQQLQVGPVPGQGPGSHRGGGGGGPPGAPPGSGGPGPSGAGSLSSLGNAVAAA 136
            |   ...:.|.|||.||..||                         ...:|.|.:|
 Worm   139 S---LRDITLTQQQPLQTLPV-------------------------TSANGIGRIS--------- 166

  Fly   137 AAAAAVHHHHQMPYQMPVPRIGPPLDYPVKLEDAPGGGVRPVRISHMTPHHLPPNATRGGGGAPG 201
                        |.:.|.|.:.|                       .:|.|
 Worm   167 ------------PQRTPQPTVLP-----------------------TSPFH-------------- 182

  Fly   202 GGVPTAGSGGGSLPPALSVNLKRPPSEDVDVDVSQQQQQS----GHGLAPDGSAGNSLSAGGGVS 262
              |||..:....|.....:.:.:.....|| |:.||..:|    .|.|||
 Worm   183 --VPTMNNLEQVLTHQRLLQMTQANPRAVD-DLIQQSLRSLGPNSHLLAP--------------- 229

  Fly   263 GGCPPGIKRSAMDDPSGVGGRPPLTRGESLPAAVSYVPERQLSGLRDKQQPV---RAPSFDASTF 324
                                    .....||:.....|.::.|.  ::|:|.   :....||.|.
 Worm   230 ------------------------FMMSMLPSTTYSNPRKRESD--EEQKPEIYGKVQRGDAQTT 268

  Fly   325 KAANPIPNPIPHHLHIAEHMSPASRRNGSSPPSGPLPPRSVHSPNSSGSSSGRRSSGSRHVSSTT 389
            .|:                                  |.|.|||:..|....|
 Worm   269 TAS----------------------------------PTSTHSPDHPGVKDRR------------ 287

  Fly   390 VTSSEVGGSNPGQAVVAGGLGGGGGGGPGSNAASGQLGGPSGGSGQLSCTSGGPGGSASSGSGGN 454
                                                                             
 Worm   288 ----------------------------------------------------------------- 287

  Fly   455 GAIGPASMAPNSVAGDGSPAGGNGPSGSNGSGGSVNPGPGSSGSQGGGGGGTPLASGGGSAGSGG 519
                                                             |..|:
 Worm   288 -------------------------------------------------GIAPI----------- 292

  Fly   520 LGGAPGSSAASNSAAAAAAAAAQNATLKCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQN 584
                                   ...|:||||.||||||||||||:|:.|||||||||.|||.|
 Worm   293 -----------------------ERVLRCTLCNERLEDTHFVQCPTVSIHKFCFPCSRSSIKDQ- 333

  Fly   585 GLGNEVYCPSGDRCPLANSVIPWAFMQGEITTILGEEV-KVKKERES 630
            ...:::||||||:|||..|.:|||||||||..|||:|. :.|:.||:
 Worm   334 CKSSDMYCPSGDKCPLVGSAMPWAFMQGEIAQILGDEYDEFKRTREA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pits	NP_001138192.1	IRF-2BP1_2	6..57	CDD:463250	36/49 (73%)
		vRING-HC_IRF2BP1-like	546..602	CDD:438174	40/55 (73%)
ifbp-1	NP_506317.2	IRF-2BP1_2	75..126	CDD:463250	36/49 (73%)
		vRING-HC_IRF2BP1-like	296..351	CDD:438174	40/55 (73%)