Protein Alignment hwt and Shf

DIOPT Version :9

• Sequence 1: NP_001259484.1
• Gene: hwt / 32202
• FlyBaseID: FBgn0264542
• Length: 1768
• Species: Drosophila melanogaster
• Sequence 2: XP_008760438.3
• Gene: Shf / 362205
• RGDID: 1562705
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 160/574 - (27%)
• Similarity: 225/574 - (39%)
• Gaps: 158/574 - (27%)

  Fly  1247 AQGHQGGQSTHHHHHHHHHAP-GSRRNRHGQSQGQTTGGGHNYSSTESIATSSSGGSMESLRSST 1310
            |||..||            .| ||||...|  .|...|||            .|||..:.||
  Rat    17 AQGSAGG------------GPGGSRRGAGG--AGTAPGGG------------GSGGVAKWLR--- 52

  Fly  1311 SEGNRSTSSSESRHSSSLSSHSSESGSGGSGGSGGSSVAYPLRPAPLLLHSKLHILSPISDKSSQ 1375
                               .|....|.||.||:         :|||           |..|....
  Rat    53 -------------------EHLGFRGGGGGGGT---------KPAP-----------PEPDYRPP 78

  Fly  1376 EPASASASEQSQQPSQQLAPMASQED----DSTTSGAPAGNQVQVNASLKQPR-------SNRGA 1429
            .|..|:   ....|...||....|.|    |..:.|:      .|:|:|..|.       ...|:
  Rat    79 APCPAA---PPAPPPDILAAYRLQRDRDFEDPYSGGS------SVSAALSTPTVPGPTPPPRHGS 134

  Fly  1430 PNKALLQLADELLG-----SDSGISLHSREDGKPQALALQRLTLPKLQLIGAEGTTTSATASGAG 1489
            |...|:::  |..|     .|||          |.| :..||.:.:..   |:......|..|:|
  Rat   135 PPHRLIRV--ETPGPPAPPPDSG----------PPA-SSDRLAILEDY---ADPFDVQETGEGSG 183

  Fly  1490 GSSATGGSSGAGGSGSG------------SVVASGSTGIQQ-DLRDLPFDMPKLRRRKTLQQEAA 1541
            |   |.|::.......|            .:..|..|.:|. .|.|.|:: |: ....:|:.|.|
  Rat   184 G---TSGAAEKVPENDGYMEPYEAQKMMAEIRGSKETAVQPLPLYDTPYE-PE-DEGASLEGEGA 243

  Fly  1542 CTSGSATSVDLGELP---FDMP---KLRRRLRANQAEINNLLMHSTESSGISQASSSHSMRDDQK 1600
            .....:...:..|.|   :|.|   |..|..:|...:| .::........:.|..||.|:.|..:
  Rat   244 PWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDI-KVIKDLPWPPPVGQLDSSPSLPDGDR 307

  Fly  1601 MSSKLDTALFRQNLTLNLNESRQATKQFGSLDLRGLNSNKE----LNMNLSQGY-VTAVDL---- 1656
            ..|...:.|...:|       ..::.||...:...|:..:|    |...||.|. .||..|
  Rat   308 DISGPASPLPEPSL-------EDSSAQFEGSEKNCLSPGREEKGRLPPRLSAGNPKTAKPLGAEP 365

  Fly  1657 -------IDVTIPLERQGWYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMH 1714
                   .|..:|||.|.||||||:|.:||..||...|.|:||||.||:|.|:|||||.::||||
  Rat   366 SSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSESSKNDFSLSLKSSQGFMH 430

  Fly  1715 MRIQRNETGQYILGQFSRPFETVPEMIRHFCLNRLPVRGAEHMCLIEPVIAQLL 1768
            |::.|.:..:|:|||.|.||.:|||::.|:...:||::|||||.|:.||..:.|
  Rat   431 MKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hwt	NP_001259484.1	SH2_SHB_SHD_SHE_SHF_like	1666..1763	CDD:198198	52/96 (54%)
Shf	XP_008760438.3	SH2_SHF	382..479	CDD:198255	52/96 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000