Protein Alignment hwt and She

DIOPT Version :9

• Sequence 1: NP_001259484.1
• Gene: hwt / 32202
• FlyBaseID: FBgn0264542
• Length: 1768
• Species: Drosophila melanogaster
• Sequence 2: NP_766118.3
• Gene: She / 214547
• MGIID: 1099462
• Length: 492
• Species: Mus musculus
• Alignment Length: 612
• Identity: 133/612 - (21%)
• Similarity: 215/612 - (35%)
• Gaps: 176/612 - (28%)

  Fly  1201 PPSTNSN---SNAASASASASVSATGS-AAPRRPRSFVLESGRVLELRRSAQGHQGGQSTHHHHH 1261
            ||:..:.   |.|:|...||:.:..|. .|.:..:.|.|......|  |:..|..||:
Mouse     4 PPAPGAPRCLSWASSLFCSAASTLPGPLMAAKWFKEFPLTLKTASE--RARPGGAGGK------- 59

  Fly  1262 HHHHAPGSRRNRHGQSQGQTTGGGHNYSSTESIATSSSGG-------SMESL----RSSTSEGNR 1315
                   .|:|........|.|.|...|:.|..|:.:|.|       |.:||    :::..:|.:
Mouse    60 -------PRKNSETGGAAPTPGKGRKNSAAELGASKASSGPPKDSRLSRDSLQGLIQAAAGKGRK 117

  Fly  1316 -----STSSSESRH------SSSLSSHSS-------ESGSGGSGGSGGSSVAYPLRPAPLLLHSK 1362
                 :|::.|..|      |:..|::.|       :..:|.|...||.|
Mouse   118 NSRVTATATEEEPHRGAVTKSAGCSTYISRLIKVDTQEKNGKSAYPGGGS--------------- 167

  Fly  1363 LHILSPISDKSSQEPASASASEQSQQPSQQLAPMASQEDD-------------STTSGAPAGNQV 1414
                   :..||...:|||:|..|..|....|.:..|:|.             ..|.|.....:|
Mouse   168 -------TSSSSSSSSSASSSPSSLGPELDKAKIMRQQDTVIILEDYADPYDAKRTKGQRDAERV 225

  Fly  1415 QVNASLKQPRSNRGAPNKALLQLADELLGSDSGISLHSREDGKPQALALQRLTLPKLQLIGAEGT 1479
            ..|....:|..            |.:::     ..:..|....|...|||.|..|     ...|.
Mouse   226 GENDGYMEPYD------------AQQMI-----TEIRRRGSKDPLVKALQLLDGP-----SEPGE 268

  Fly  1480 TTSATASGAGGSSATGGSSGAGGSGSGSVVASGSTGIQQDLRDLPFDMPKLRRRKTLQQEAACTS 1544
            |....|:....||                  ....|....|.|.|::..:..:|....:.....|
Mouse   269 TVKVEATAKRRSS------------------KDLLGKPPQLYDTPYEPSEGGQRVAEVKTRPADS 315

  Fly  1545 GSATSVDLGELPFDMP---KLRRRLRANQAEINNLLMHSTESSGISQASSSHSMRDDQKMSSKLD 1606
            ......|.....::.|   |..:..||...:...    |....|...|...|.
Mouse   316 RLPEEDDRPAAEYEQPWEWKREQIARALSVQFEG----SDRPPGREDAGRPHH------------ 364

  Fly  1607 TALFRQNLTLNLNESRQATKQFGSLDLRGLNSNKELNMNLSQGYVTAVDLIDVTIPLERQGWYHG 1671
               :::.|...|::.....|                              :|..:.||:|.||||
Mouse   365 ---WQKTLKPTLSDHGDGEK------------------------------VDPGLALEKQPWYHG 396

  Fly  1672 AITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNETGQYILGQFSRPFET 1736
            :|:|.|||:.|:|..|.::||||.||....||::||.::|.:|:.:.:.:..:|.|.|.|..|::
Mouse   397 SISRAEAESRLQPCKEAAYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDS 461

  Fly  1737 VPEMIRHFCLNRLPVRGAEHMCLIEPV 1763
            :||::.::...:||.:|||||.|:.||
Mouse   462 IPEVVHYYSNAKLPFKGAEHMTLLHPV 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hwt	NP_001259484.1	SH2_SHB_SHD_SHE_SHF_like	1666..1763	CDD:198198	40/96 (42%)
She	NP_766118.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..193		38/184 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..236		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..332		14/94 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	347..384		7/85 (8%)
		SH2_SHE	391..488	CDD:198254	40/96 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M87
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001120
OrthoInspector	1	1.000	-	-		otm42570
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.870