Protein Alignment Mks1 and mks1

DIOPT Version :9

• Sequence 1: NP_572804.1
• Gene: Mks1 / 32200
• FlyBaseID: FBgn0030395
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001070841.2
• Gene: mks1 / 556706
• ZFINID: ZDB-GENE-030131-3813
• Length: 559
• Species: Danio rerio
• Alignment Length: 658
• Identity: 147/658 - (22%)
• Similarity: 249/658 - (37%)
• Gaps: 205/658 - (31%)

  Fly   105 ISQHEGEMEKDKNEGEITDLESQSNRSWSILSDNSRPPAGDLFYKRNKELCNGAIATIRISWQQK 169
            :|:|..:....:.|..:.:||:.|.::.|...:              :||.        ::||:|
Zfish    38 LSEHLHQQVLSQQERGVIELETFSTQTASSTDE--------------EELV--------VAWQEK 80

  Fly   170 HFSQAELEQYINNPGSCASKLQRRYHRWALETLKLQQRYLRKLENLEDAETVEDPEPITIRRRIR 234
            .|||.|::.| ....:|.:.|:|:||...:...:.::|..:::....|.:            |..
Zfish    81 FFSQYEVDLY-QTESNCQTPLERQYHTDIMAMERSKRRQNQRIFTYTDFD------------RFS 132

  Fly   235 KPKAKQRGCSAAAHPTITSLSSANMSEVSILDDPNFAARTCLIHTLLDNDSESLMPAEAS----- 294
            |.:.:.:.....|.||.|.|:. .|:.|.                   :..:...|||::
Zfish   133 KWEEQAQSLVIPAQPTPTFLAE-RMANVR-------------------HRRQERRPAESNVPKSR 177

  Fly   295 --------EFHKKGY------QLMYIYADL---------QQDTLLVSIRYDPEQGLLYVYPDFSS 336
                    ||.|..:      |.|||.|||         :.:.:|.:|:.| ..|::.:.|||::
Zfish   178 LITWEPSEEFVKNSHIINTPVQTMYIMADLGPTGKLGLKENEYVLCTIKAD-GNGVISIKPDFNN 241

  Fly   337 SAQDLDYVIQIERNNDCRQLYAFGFENVTPLEAYDDDGFSEEADGEDEQELGDGLPIEEDLPEEA 401
            :..    ..::|...:.|:::....||.:      .|..:||.|.|..        :..||
Zfish   242 NRG----AYRLETEGEKREVWRLYLENAS------SDIQAEEKDREQR--------MYRDL---- 284

  Fly   402 SAEEILEFYRRRREAASERRSLL--QFEMPPKRMKRVSLLLELQEGQNFENPNIHVRYYLKAPAN 464
                    |.|.::..:   ||:  .|||||..:.|:.:..|:...|.:|..|::|.:::..|.|
Zfish   285 --------YTRHKDYLN---SLVGQDFEMPPPGILRLIVNGEIVSAQGYEYDNLYVHFFVDLPNN 338

  Fly   465 TFYEGTPGVDTMQGATATCRNAGDWRS------AHLGHCWQV-TLLLEEQHHPADLLH---LYFE 519
            .   .:.....:.|.|.|||.    ||      |...:.:.. |...:|......|..   |||:
Zfish   339 W---SSVSSHCLSGVTQTCRT----RSIEKEDVAFFSYPFSFETFFHKEDESDGSLPQWPVLYFK 396

  Fly   520 VISIDSWQRERCEGYAHYAIPLTSALPTDSIRLQCIRPLGNW-------LDALNRYFIGGRQLFD 577
            |:|:|.|||.|.|||.:..||.||.    ..|:.|    ..|       :..|.|:||||....:
Zfish   397 VLSLDFWQRFRTEGYGYLVIPSTSG----RHRMTC----RTWRAVQRGTVAELRRFFIGGAPELE 453

  Fly   578 FESFFDVHR--QSEMHSRLNFNSDRPMTTTGTLSLRLQKLQQRQ--IDTS----------DQFHH 628
            ..|:..:..  :.|..||..|.:.    |||:::..|..:|..:  ||.|          ||...
Zfish   454 DISYVRIPGTFKGERLSRFGFRTQ----TTGSVTFTLNCIQHARAFIDASTLKKRRQTVLDQLGG 514

  Fly   629 HFHLELGNDSSDDGDSNDDDVRSSSNPDTSRATTLDEVMAAFVEARKRIEL--------LLGNSS 685
            |                            |:..::..|:.||..|.||::.        |:..|:
Zfish   515 H----------------------------SQQGSVYNVLEAFQRAHKRMQEARETLPRDLINTSA 551

  Fly   686 ETASPSSA 693
            ...|.|||
Zfish   552 LLNSESSA 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mks1	NP_572804.1	B9-C2	442..613	CDD:284557	51/189 (27%)
mks1	NP_001070841.2	B9-C2	316..488	CDD:284557	52/190 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4446
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091079at2759
OrthoFinder	1	1.000	-	-		FOG0008038
OrthoInspector	1	1.000	-	-		oto39945
orthoMCL	1	0.900	-	-		OOG6_104799
Panther	1	1.100	-	-	LDO	PTHR12968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5743
SonicParanoid	1	1.000	-	-		X5993
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790