Protein Alignment Rab40 and RAB28

DIOPT Version :9

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001017979.1
• Gene: RAB28 / 9364
• HGNCID: 9768
• Length: 221
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 64/233 - (27%)
• Similarity: 103/233 - (44%)
• Gaps: 49/233 - (21%)

  Fly     9 DYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTT--------TILLEG 65
            |..||::::||...||..:.:                |.:.......||.|        .|.|.|
Human    10 DRQLKIVVLGDGASGKTSLTT----------------CFAQETFGKQYKQTIGLDFFLRRITLPG 58

  Fly    66 K-RVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW---LKEVDEHAPGIPK 126
            . .|.||:||..||.....::..|..||||::|||||||..||:.::.|   :|:|.|.:...|.
Human    59 NLNVTLQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPL 123

  Fly   127 V-LVGNRLHLAFKRQVAAKQAETYASRNNMSCFEISP-------LCNFNIRESFCELARMALHRN 183
            | ||||::.|...|.:..::...:...|..|...:|.       ||   .::...|:..:.|::.
Human   124 VALVGNKIDLEHMRTIKPEKHLRFCQENGFSSHFVSAKTGDSVFLC---FQKVAAEILGIKLNKA 185

  Fly   184 GMEHIWRSNKVLSL------QELCCRTI-VRRTSVYAI 214
            .:|   :|.:|:..      ||...||: ..|:|:.|:
Human   186 EIE---QSQRVVKADIVNYNQEPMSRTVNPPRSSMCAV 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	64/233 (27%)
		RAB	12..182	CDD:197555	53/189 (28%)
		SOCS	192..234	CDD:295349	8/30 (27%)
RAB28	NP_001017979.1	Rab28	13..221	CDD:206694	63/230 (27%)
		Effector region. /evidence=ECO:0000250	41..49		3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900