Protein Alignment Rab40 and RAB33B

DIOPT Version :10

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_011530601.1
• Gene: RAB33B / 83452
• HGNCID: 16075
• Length: 277
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 63/197 - (31%)
• Similarity: 104/197 - (52%)
• Gaps: 28/197 - (14%)

  Fly    11 LLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGN--DCTSHILQTVAYKTTTILLEGKRVKLQLW 73
            :.|::::|||:|||..:...         ||:|.  |.|...: .|.::...:.::|:|:|:|||
Human    81 IFKIIVIGDSNVGKTCLTYR---------FCAGRFPDRTEATI-GVDFRERAVEIDGERIKIQLW 135

  Fly    74 DTSGQGRF-CTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEH--APGIPKVLVGNRLHL 135
            ||:||.|| .::::.|.|....::.|||:||..||..:..|::|..:|  |..||::||||:..|
Human   136 DTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDL 200

  Fly   136 AFKRQVAAKQAETYASRNNMSCFEIS---PLCNFNIRESFCELARMALHRNGMEHIWRSNKVLSL 197
            ....||....|:.:|..::|..||.|   |..|.::...|..||          |..:|:|.|.|
Human   201 RSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLA----------HKLKSHKPLML 255

  Fly   198 QE 199
            .:
Human   256 SQ 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop containing Nucleoside Triphosphate Hydrolases	6..265	CDD:476819	63/197 (32%)
		SOCS	192..234	CDD:470605	3/8 (38%)
RAB33B	XP_011530601.1	Rab33B_Rab33A	80..249	CDD:133315	59/187 (32%)