DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and RABE1c

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001078248.1	Gene:	RABE1c / 823749	AraportID:	AT3G46060	Length:	216	Species:	Arabidopsis thaliana

Alignment Length:	174	Identity:	73/174 - (41%)
Similarity:	104/174 - (59%)	Gaps:	12/174 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQT-VAYKTTTILLEGKRVKL 70
            |||||:|:||:|||.|||..:|....|         |:..||.|... :.:|..||.|:|||:||
plant    11 DYDYLIKLLLIGDSGVGKSCLLLRFSD---------GSFTTSFITTIGIDFKIRTIELDGKRIKL 66

  Fly    71 QLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-PGIPKVLVGNRLH 134
            |:|||:||.||.||..:|.|||.||:||||:|::.||:.|..|::.:::|| ..:.|:||||:..
plant    67 QIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQHASDNVNKILVGNKAD 131

  Fly   135 L-AFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELAR 177
            : ..||.|...:.:..|....:..||.|...|.|:.|.|..:.|
plant   132 MDESKRAVPTAKGQALADEYGIKFFETSAKTNLNVEEVFFSIGR 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	73/174 (42%)
		RAB	12..182	CDD:197555	68/169 (40%)
		SOCS	192..234	CDD:295349
RABE1c	NP_001078248.1	Rab8_Rab10_Rab13_like	13..180	CDD:206659	71/172 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910