Protein Alignment Rab40 and Rab11b

DIOPT Version :10

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_116006.1
• Gene: Rab11b / 79434
• RGDID: 68369
• Length: 218
• Species: Rattus norvegicus
• Alignment Length: 230
• Identity: 80/230 - (34%)
• Similarity: 123/230 - (53%)
• Gaps: 35/230 - (15%)

  Fly     1 MGTMTKDYDYLLKVLLVGDSDVGKHEILS-------NLEDPSTESPFCSGNDCTSHILQTVAYKT 58
            |||...:||||.||:|:|||.|||..:||       |||..||..               |.:.|
  Rat     1 MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIG---------------VEFAT 50

  Fly    59 TTILLEGKRVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-P 122
            .:|.::||.:|.|:|||:||.|:..|..:|.|||.|.:|||||....:::.::|||||:.:|| .
  Rat    51 RSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS 115

  Fly   123 GIPKVLVGNRLHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHRNGMEH 187
            .|..:||||:..|...|.|...:|..:|.:||:|..|.|.|.:.|:.|:|         :|.:..
  Rat   116 NIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAF---------KNILTE 171

  Fly   188 IWRSNKVLSLQELCCRTIVRRTSVYAIDSLPLPPS 222
            |:|   ::|.:::..|.....:....:..:.:||:
  Rat   172 IYR---IVSQKQIADRAAHDESPGNNVVDISVPPT 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop containing Nucleoside Triphosphate Hydrolases	6..265	CDD:476819	77/225 (34%)
		SOCS	192..234	CDD:470605	4/31 (13%)
Rab11b	NP_116006.1	Rab11_like	9..173	CDD:206660	70/187 (37%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q15907	36..47		5/25 (20%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q15907	67..86		9/18 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..218		3/20 (15%)