DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and rab44

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_689291.6	Gene:	rab44 / 560799	ZFINID:	ZDB-GENE-040724-117	Length:	2402	Species:	Danio rerio

Alignment Length:	194	Identity:	57/194 - (29%)
Similarity:	89/194 - (45%)	Gaps:	16/194 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKT--TTILLEGKRVKLQLWDTS 76
            |::||:|.|||...:....    |..|      |.....|:...|  .|:.|..:.||||:|||:
Zfish  2220 VVMVGNSCVGKTSFIRRFH----EGQF------TEDYRSTIGVDTFVQTVELPDRTVKLQIWDTA 2274

  Fly    77 GQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-PGIPKVLVGNRLHLAFKRQ 140
            ||.||.:|.......|:|::|:|:||...||..|..|:.:..|.| ..:..:|:||: :.:..|:
Zfish  2275 GQERFHSITTQVFHKAEGLLLMYEITCSKSFISIRDWISQARERAQDDVVMMLLGNK-NDSVNRE 2338

  Fly   141 VAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHRNGM--EHIWRSNKVLSLQELCC 202
            |..::....|...|:...|.|.....|:.||...||.:.:.|...  ||.....:....:..||
Zfish  2339 VQIQEGADLAREYNIHFMECSAANGANVSESMRTLAELLVQRKRKREEHTTLRREPQQKKSGCC 2402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	57/194 (29%)
		RAB	12..182	CDD:197555	52/170 (31%)
		SOCS	192..234	CDD:295349	2/11 (18%)
rab44	XP_689291.6	EIN3	<1419..>1534	CDD:296674
		RAB	2218..2380	CDD:197555	52/170 (31%)
		Rab	2218..2375	CDD:206640	51/165 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900