DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and RabX4

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster

Alignment Length:	178	Identity:	69/178 - (38%)
Similarity:	100/178 - (56%)	Gaps:	14/178 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MTKDYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCS--GNDCTSHILQTVAYKTTTILLEGK 66
            |..|:....|||::|||:|||..|:....|......:.|  |.|          :|...|.|:|.
  Fly     1 MALDFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGID----------FKQKLINLDGV 55

  Fly    67 RVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-PGIPKVLVG 130
            .:|||:|||:||.||.|:..:|.|||.||:|:||:||..|::.:..||:.:.|:| |.:.|||.|
  Fly    56 PIKLQIWDTAGQERFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAG 120

  Fly   131 NRLHL-AFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELAR 177
            |:... |.:|.|..::.|..|...:|..||:|...|.||.::|..|||
  Fly   121 NKCECSATQRMVDKERGEKIAENFDMPFFEVSCKSNINIEDAFLSLAR 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	68/176 (39%)
		RAB	12..182	CDD:197555	67/170 (39%)
		SOCS	192..234	CDD:295349
RabX4	NP_733043.1	RAB	9..170	CDD:197555	67/170 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910